Neha Singh, Dayalbagh Educational Institute, India
Pervasive use of pesticides in all over the word that may affect human nervous system extensively. Likewise pyrethroids are the major group of pesticides that is used in household products from where human get affected and suffer with various neurological disorders such as Parkin [....] » Read More
Title : Prognostic indicators of spontaneous neurological recovery following Traumatic Spinal Cord Injuries and the role of the Neurologist
W S El Masri, Keele University, United Kingdom
Spontaneous Neurological Recovery is very common in patients with incomplete traumatic spinal cord injuries. This is provided no further mechanical and non-mechanical damage is inflicted onto the injured cord. Currently there is great deal of emphasis on the threats of the Biomec [....] » Read More
Title : The case of jahi mcmath: Dilemmas and controversies in the diagnosis of brain death
Calixto Machado, Institute of Neurology and Neurosurgery, Cuba
I was a main expert in the case of Jahi McMath, who was diagnosed with brain death (BD). Nonetheless, ancillary tests performed nine months after the initial brain insult showed conservation of intracranial structures, EEG activity, and autonomic reactivity to the “Mother T [....] » Read More
Title : Rogue Percepts = Rogue Responses: What Are the Possible Sets of Initial Conditions That Give Rise to Willis-Ekbom Disease - Restless Legs Syndrome (RLS), And Can RLS be Therapeutically Pacified? - A NeuroPhysics Therapy Study and Hypothesis Based Upon Observations and Outcomes -
Ken Ware, NeuroPhysics Therapy Institute and Research Centre, Australia
The human central nervous system (CNS) fundamentally does something elegant and simple and is programmed to abide by some simple sets of rules and initial conditions. Fundamentally, the CNS takes in and perceives information coming in from the outside world and responds to it. Ho [....] » Read More
Title : Investigating novel therapies for metachromatic leukodystrophy, a fatal neurodegenerative disease
Marianna Mekhaeil, Trinity college Dublin, Ireland
Metachromatic leukodystrophy (MLD) is a rare genetic disorder that affects the central nervous system white matter. MLD is caused by recessive mutations in ARSA encoding arylsulfatase A. Low activity of arylsulfatase A results in the accumulation of sulfatides in the central and [....] » Read More
Title : Application of activity-based probe, MV151, in the mammalian nervous system reveals new insight into proteasome changes in human Alzheimer’s disease brain
Fulya Turker, Johns Hopkins University School of Medicine, United States
Proteasome complexes play a critical role in human brain health and disease. Despite enormous effort, a deep understanding of proteasome composition, activity, and abundance in the human brain remains poorly understood. Here, we describe a series of tools that can measure the cat [....] » Read More
Title : Studies with the use of the Hyperbaric Oxygen Therapy (HBOT) and its influence on cerebral Neuroplasty: Effects after ischemic and hemorrhagic stroke.
Jose Iranildo Sales, Mauricio de Nassau University of Medicine, Brazil
Background: Recent studies have raised the possibility and clinical feasibility of using treatments using oxygen therapies in hyperbaric chambers (HBOT) for the analysis of functional and cognitive improvements in patients after ischemic and hemorrhagic strokes. The effects in ce [....] » Read More
Title : Treatment with novel Hippo Signaling inhibitor, Xmu-mp-1, ameliorates cognitive impairments in sporadic Alzheimer Disease rats
Manas Ranjan Sahu, Jawaharlal Nehru University, India
Alzheimer's disease (AD), the most common form of dementia, is a progressive neurodegenerative disorder associated with aging. Persons with Alzheimer's face some serious problems associated with memory, thinking, motor movements, language, and behavior due to neurodegen [....] » Read More
Title : The Importance of Writing as a (Cognitive) Therapy Aid To help Determine a Stroke Survivors' Journey of Discovery
Simon Barton, Talking Magnets LLC, United States
Those of us fortunate enough to have survived a (massive) stroke event often embark on the post-stroke “journey of recovery” without the correct tools to properly manage it. We will hear and retain certain messaging repeatedly, for example, “I cannot tell you h [....] » Read More
Title : Studies with the use of the hyperbaric oxygen therapy (HBOT) and its influence on cerebral neuroplasty: Effects after ischemic and hemorrhagic stroke
Maria Gerliane Cavalcante, Mauricio de Nassau University of Medicine, Brazil
Background: Recent studies have raised the possibility and clinical feasibility of using treatments using oxygen therapies in hyperbaric chambers (HBOT) for the analysis of functional and cognitive improvements in patients after ischemic and hemorrhagic strokes. The effects in ce [....] » Read More
Title : Inside the Mind of a 32 year old Stroke Survivor Living with Moya Moya Disease
Michelle Herman, Michelle Herman Speaks, United States
At the age of 32, and 6 months postpartum from having her first child, Michelle walked into the ER with impaired motor skills on the left side of her body, a horrible headache and slurred speech. She was diagnosed with a migraine and discharged. Two days later she had a massive I [....] » Read More
Title : Energetics and emergent calcium dynamics in an astrocyte-neuronal network coupled via nitric oxide molecule
Bhanu Sharma, Delhi University, India
Neurons and glial cells work in conjunction with each other during information processing in brain. Stimulation of neurons can cause calcium oscillations in astrocytes which in-turn can affect neuronal calcium dynamics. The “glissandi” effect is associated with a decr [....] » Read More
Title : Multi-Characteristic Opsin Gene Delivery for Neuromodulation of Inflammatory and Persistent Pain Sensation in Rodent Model
Arman John Fijany, TCU School of Medicine, United States
Pain is an uncomfortable sensation perceived by the nervous system that can have a variety of different causes. Pain can be seen as a complication of disease, emotional states and even as a standalone pathology. The neuroscience of pain is poorly understood. Multiple levels of co [....] » Read More
Title : Lived Experience of the African American Informal Caregivers of a Family Member with Alzheimer’s Disease and Related dementia
Dell G Mars, Southeastern Louisiana University School of Nursing, United States
Purpose: The purpose of this qualitative study was to describe the lived experience of African American informal caregivers of family members of Alzheimer’s Disease and Related Dementias (ADRD) in a home environment. Design and Method: This phenomenological descriptive [....] » Read More
Title : Screening Of Biomarkers For Acute Ischemic Stroke Using Bioinformatics Analysis
Lakshmi Sundeep, Hindustan Institute of Technology and Science, India
Acute Ischemic Stroke (AIS) is a life-threatening cerebrovascular illness. The cause of AIS is unknown, and treatment options are limited. The study is to find out which genes are expressed in AISs and use that information to guide future research and treatment. The raw datasets [....] » Read More
Title : In vitro modelling of brain development and neurodegenerative diseases
Andreas Till, University of Bonn, Germany
Given the complex etiopathology of neurodegenerative diseases and the limited access to vital human brain cells as suitable research platform, there is an increasing demand of innovative human-specific model systems that help elucidating the causative mechanisms of these disorder [....] » Read More
Title : Immunogenetic Detection of Alzheimer’s Disease
Rizwan Khan, Western Sydney University, Australia
Alzheimer’s disease (AD) is on a rapid rise in the aged population with typical hallmarks of extracellular Aβ deposits and intracellular neurofibrillary tangles (NFT) composed of hyperphosphorylated tau proteins. Positron emission tomography imaging and screening for A [....] » Read More
Title : Nanocarrier Based Brain Delivery of Camelid Derived Antibodies For The Treatment Of Alzheimer's Disease
Sachin Kumar, Western Sydney University, Australia
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, clinically characterised by progressive impairment of memory, cognitive ability, and behavioural changes. As per World Health Organisation statistics 55 million people are currently living with dementia. [....] » Read More
Title : The MS and HSV look-alike: A case report on neuromyelitis optica
Brandon William Moritz, University of Oklahoma College of Medicine, United States
A 23-year-old Caucasian male with a past medical history of anxiety, pilonidal cyst removal from the lower back in 2 years ago, and EBV infection 1 month ago presents to an on-campus eye institute after 1 week of binocular diplopia, headache, intermittent muscle weakness, neck so [....] » Read More
Title : The apt diagnosis of progressive supranuclear palsy with frontal predominance: A case report
Solomon Nittala DO MS, Larkin Community Hospital Palm Springs Campus, United States
Originally described in 1964, progressive supranuclear palsy (PSP) is a neurodegenerative tauopathy with a prevalence of approximately 45% among other parkinsonian-plus syndromes. PSP can be categorized into various phenotypes among which 6% belong to the PSP-frontal predominan [....] » Read More
Title : A rare case of neurotoxoplasmosis in an immunocompetent elderly patient
Maria R Cochran Perez, Universidad Central del Caribe Internal Medicine Residency Program, Puerto Rico
Introduction Neurotoxoplasmosis is an infection caused by Toxoplasma gondii, an intracellular protozoan that is often associated with immunocompromised patients, being rare in immunocompetent patients and often undetected. Toxoplasmosis is an obligate intracellular, food-borne [....] » Read More
Title : A headache that makes a grown man cry: Cerebral sinus thrombosis secondary to coronavirus disease 2019
Ana Martes Bermúdez, UCC Internal Medicine Residency Program, Puerto Rico
Introduction: There have been increasing reports associating coronavirus disease 2019 (COVID-19) with thromboembolic phenomenon including cerebral venous thrombosis (CVT), which is a rare neurovascular emergency often found in critically ill patients, yet its true incidence [....] » Read More
Title : Could We See Alzheimer’s Disease Through the Eye?
Aygun BadaLova, University College London, United Kingdom
One of the most common and prevalent neurodegenerative disorders are Alzheimer's and Dementia which are considered significant causes of mortality and morbidity in today’s society particularly among the elderly population.(Erkkinen, Kim et al. 2018)The etiologic and pat [....] » Read More
Title : COVID Infection and the Surprise Guillain Barre Syndrome Diagnosis
Neil Gerts, Los Robles Regional Medical Center, United States
The World Health Organization declared COVID-19 a pandemic in February 2020, and it has affected the life of each and everyone. COVID-19 is designated as severe respiratory syndrome coronavirus 2 (SARS-CoV-2). It causes an acute inflammatory process in the body, which is hypothes [....] » Read More
Title : Assessment Of Knowledge And Practices And Impact Of Intervention About Early Diagnosis And Management Of Increased Intracranial Pressure Among Residents And Nurses Working At Tash
Firaoly Workneh, St Paul hospital millennium medical college, Ethiopia
Background Increased intracranial pressure is a common and possibly fatal complication of neurologic and systemic diseases. Diagnosis is made mainly based on clinical and neuroimaging findings. There are medical and surgical treatment options. Early diagnosis and prompt [....] » Read More
Title : The Association between Intolerance of Uncertainty with Social Interaction Anxiety and Performance Anxiety - Mediating Factors
Flavia I Spiroiu, McMaster University, Canada
BACKGROUND: Despite the potential importance of intolerance of uncertainty (IU) as a transdiagnostic feature that may contribute specifically to social anxiety, empirical data on the construct has been relatively scant and focused largely on Generalized Anxiety Disorder (GAD) and [....] » Read More
Title : Investigation of low frequency thalamic and pallidal local field potential correlation with voluntary movement in children with dystonia
Maral Kasiri, University of California, United States
Understanding the relationship between neural activity and voluntary movement provides new insights into understanding the mechanism underlying neural control of movement in both healthy people and those with movement disorders. To investigate the relationship between deep brain [....] » Read More
Title : Improving Stroke Quality Metrics at Robert Packer Hospital
Rebecca Lees, Guthrie Robert Packer Hospital, United States
Stroke is the number one preventable cause of disability and a leading cause of death in both men and women; rapid assessment and treatment is critical to improve outcomes for patients. Guthrie Robert Packer Hospital received The Joint Commission Primary Stroke Center certificati [....] » Read More
Title : Multiple Autoimmune Syndrome: Combination of Neuromyelitis Optica Spectrum Disorder with Myastenia Gravis, Systemic Lupus Erythamatosis and Hashimato Tiroiditis
Vildan Tuncbilek, Tekirdağ Namık Kemal University, Turkey
Autoimmunity reflects an altered immune status, therefore the presence of more than one disorder is not uncommon. The coexistence of three or more autoimmune diseases in a patient constitutes multiple autoimmune syndrome (MAS). This is an interesting case of a middle-aged female [....] » Read More
Title : NF-kB is a critical mediator of age-dependent white matter loss
Judith Stefanie Scheller, Institute of Physiological Chemistry, Ulm University, Germany
Inflammaging represents an accepted concept where the immune system shifts to a low-grade chronic proinflammatory state without overt infection upon aging. In the CNS, inflammaging is mainly driven by glia cells and associated with neurodegenerative processes. White matter degene [....] » Read More
Title : Cognitive and Behavioral Mechanisms of Transcranial Direct Current Stimulation in Obsessive-Compulsive Disorder
Flavia I Spiroiu, McMaster University, Canada
Background. Obsessive-compulsive disorder (OCD) is a common and severe psychiatric disorder. Cognitive behavior therapy (CBT) with exposure and response prevention (ERP) is the gold standard intervention for OCD, but more than 40% of patients with this disorder remain impaired ev [....] » Read More
Title : Gait and balance among people with de novo vs. mild to moderate Parkinson’s disease
Beata Lindholm, Lund University, Sweden
We have investigated how a de novo cohort of people with Parkinson’s disease (PD) differs in terms of balance and gait function as well as frequency of near falls and falls in comparison to a cohort with mild to moderate PD that has been medicated for several years. Prelimi [....] » Read More