HYBRID EVENT: You can participate in person at Orlando, USA or Virtually from your home or work.

6th Edition of International Conference on Neurology and Brain Disorders

October 24 -26, 2022

October 24 -26, 2022 | Orlando, Florida, USA
INBC 2022

Annapurna Ahuja

Speaker at Neurology and Brain Disorders 2022 - Annapurna Ahuja
Hazaribag College of Dental Sciences and Hospital, India
Title : Periodontitis and Neurodegenerative disorders. A possible Link

Abstract:

Neurodegenerative diseases are a group of progressive disorders that  affect the central nervous system (CNS) such as Alzheimer, Parkinson, and multiple sclerosis. Inflammation plays a critical role in the onset and progression of these injuries. Periodontitis is considered an inflammatory disease caused by oral biofilms around the tooth-supporting tissues, leading to a systemic and chronic inflammatory condition. Among the different types of neurodegenerative diseases, Alzheimer’s disease (AD), Huntington’s disease, Parkinson’s  disease (PD), and multiple sclerosis are the most frequently occurring (Hussain et al., 2018). These disorders damage the CNS and trigger rapid microglial activation, the main component of neuroinflammation. Activated microglia produce and secrete inflammatory mediators, such as eicosanoids, cytokines, chemokines, reactive free radicals, and proteases. Although a well-regulated inflammatory process is beneficial for injured CNS tissue, an excessive inflammatory response can be a source of additional injury and may affect the chronic progression of these diseases (Gao and Hong,2008).

Robust evidences has indicated a correlation between PD and systemic diseases such as cardiovascular disease, adverse pregnancy outcome, chronic kidney disease and diabetes mellitus. However, the correlation between teeth loss and the risk of neurodegenerative disorders are still under investigation. The conditions of periodontal disease (bacterial infection and chronic inflammation) weaken the blood-brain barrier and pose a risk for cerebrovascular disease. The conditions also cause inflammation in the brain. Periodontal disease may indirectly make neurodegenerative disorders  worse through exacerbation of diabetes. Furthermore, tooth loss leads to deterioration of cognitive function. Therefore, it is possible that periodontal disease directly and indirectly exacerbates the condition of these disorders.

What will audience learn from your presentation?

  • Learning the importance of oral hygiene and effects of periodontitis on systemic health.
  • Audience shall learn about the effects of oral microorganisms on nervous system.
  • Along with seeking treatment for neurodegenerative diseases one should consider visiting oral health specialist.

 

Biography:

Professor Dr. Annapurna Ahuja, studies her Masters of dental surgery from the prestigious college of dental science and hospital, affiliated to Rajiv Gandhi University of health sciences, Bangalore in 2009. She then joined Dental College as a Teaching Faculty. She has published more than 40 research articles, 8 text books of her specialty, one chapter contribution. She is a very active part of the research and has 4 copyrights of her work in the field of Periodontics. She is also a renowned poet, has written more than 200 poems. Has a recipient of Best book award for her debut book, BAPUJI written in Indian Language. Presently she is associated with Hazaribag College of Dental Sciences & Hospital, as Head of the Department, Dept. of Periodontics & Oral Implants. 

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