Title : Evaluation of the Reddesa chart, a new red desaturation testing method, for optic neuritis screening and grading in clinical routine
Background. Optic neuritis and optic neuropathy can cause a reduced color-sensitivity. Therefore, in clinical routine the patient's perception of the red color is tested in order to evaluate the function of the optic nerve. Red desaturation is traditionally tested by presenting an object of red color to the patient (red cup test). The purpose of this study was to evaluate the potential of a new red desaturation test based on polarization we created, the Reddesa chart, as a screening method for optic neuropathy.
Methods: For this monocentric prospective pilot study, 20 patients with unilateral optic neuritis and an equal number of healthy controls were included. In all participants the best corrected visual acuity (BCVA) was assessed, slit lamp examination of the anterior and posterior eye segments was performed, and the relative afferent pupillary defect (RAPD) and the red desaturation with the red cup test and the Reddesa chart was tested.
Results: The mean BCVA in the optic neuritis group was 0.76±0.36 in the affected eye (95% of eyes with RAPD, 75% of eyes with difference in the Reddesa test) and 1.28±0.24 in the healthy eye, while in the control group BCVA was 1.14±0.11 in the right eye and 1.15±0.14 in the left eye (none of the eyes with RAPD or abnormal Reddesa test). The Reddesa chart test demonstrated a positive predictive value of 100% and a negative predictive value of 80% for detecting optic neuritis.
Conclusion: The Reddesa chart is a useful tool to more objectively test and possibly quantify red desaturation in clinical routine.
What will audience learn from your presentation?
- An easy and practical solution to test red desaturation by all kind of medical personnel and not only by ophthalmologists or neurologists
- A more objective way to test for red desaturation
- A potential way to quantify red desaturation