4th International Conference on Neurology and Brain Disorders

September 09-11, 2021

September 09 -11, 2021 | Virtual Event

INBC 2017

Speaker at International Conference on Neurology and Brain Disorders 2017 - Sergi Ferre
Keynote Presentation
Sergi Ferre, National Institute on Drug Abuse (NID, NIH), United States

It has been the general assumption for several decades that the three elements of the most studied transmembrane cell signaling pathway, G protein-coupled receptors (GPCRs), G proteins and adenylyl cyclase (AC), are freely mobile molecules within the plasma membrane that interact [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Marisela Morales
Keynote Presentation
Marisela Morales, National Institute on Drug Abuse (NID, NIH), United States

Ventral tegmental area (VTA) dopamine neurons are theorized to play distinct roles in positive and negative reinforcement, decision-making, working memory, incentive salience, and aversion. This behavioral heterogeneity is reflected in part in the diverse phenotypic characteristi [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Steven Benvenist
Oral Presentation
Steven Benvenist, United States Civil Attorney and Partner at Davis, United States

Attorney Steven Benvenisti will share the captivating story of a famous case involving a college student who sustained severe traumatic brain injuries and catastrophic orthopedic injuries, resulting in his family being asked to consent his organ donation. “Spring Break&rdqu [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Michel Baudry
Oral Presentation
Michel Baudry, Western University of Health Sciences, United States

Numerous reviews have discussed the role of calpain in neurodegeneration in general, and in stroke and Traumatic Brain Injury (TBI). Consequently, numerous studies have attempted to use calpain inhibitors to reduce neurodegeneration in both stroke and TBI. While some studies have [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Miranda N. Reed
Oral Presentation
Miranda N. Reed, Auburn University, United States

A body of clinical evidence has demonstrated that viral infections in the periphery exacerbate neurodegenerative conditions, e.g., multiple sclerosis, Parkinson disease, Alzheimer Disease (AD), and seizures. For example, peripheral infections increase the propensity and severity [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Stephen Wren
Oral Presentation
Stephen Wren, University of Oxford, United Kingdom

The Alzheimer’s Research UK Oxford Drug Discovery Institute combines the deep disease knowledge and biology expertise of Oxford University with high quality, innovative drug discovery technologies and expertise to identify new ways of treating neurodegeneration. Our capabil [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - KHIN MAUNG BO
Oral Presentation
KHIN MAUNG BO, Northern Lincolnshire and Goole NHS Foundation Trust, United Kingdom

Abstract: Demyelination affects highly myelinated structures like Corpus Callosum (CC). CC is unique in function that it connects right and left hemisphere. It synchronises bimanual or bipedal activities. Affecting CC can disturb synchrony between the two hemispheres will affect [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Mahmoud Kiaei
Oral Presentation
Mahmoud Kiaei, University of Arkansas for Medical Sciences, United States

Mutations in profilin1 (PFN1) have been shown to cause Amyotrophic Lateral Sclerosis (ALS) in human patients, however the molecular mechanisms responsible for this effect are unknown. To study profilin1 neurotoxicity and the mechanism of neurodegeneration, transgenic mice overexp [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Michael Ugrumov
Oral Presentation
Michael Ugrumov, Institute of Developmental Biology RAS, Russian Federation

Motor symptoms first appear in Parkinson’s disease (PD) years after beginning of degradation of the nigrostriatal dopaminergic system at loss of threshold amount of dopamine (DA) in the striatum (70%), which explains low efficiency of treatment. Therefore, the development o [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Kimiko Inoue
Oral Presentation
Kimiko Inoue, Toneyama National Hospital, Japan

Neuronal intermediate filament inclusion disease (NIFID) is a rare neurodegenerative disorder which is a type of frontotemporal lobar degeneration (FTLD) with various clinical features including frontotemporal dementia and pyramidal and extrapyramidal signs occurring at a young a [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Caroline Corbel
Oral Presentation
Caroline Corbel, Institut de Recherche Dupuy de Lôme (IRDL), France

Cyclin-dependent kinase 5 (CDK5) is a multifunctional enzyme that plays numerous roles, notably in brain development. CDK5 is activated through its association with the specific activators, p35 and p39. Proteolytic procession of the N-terminal part of its activators has been link [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Jong Wook Chang
Oral Presentation
Jong Wook Chang, Samsung Medical Center, Korea, Republic of

Various groups have presented findings that human mesenchymal stem cells (MSCs) have both immunomodulatory and trophic properties. MSCs tend to act indirectly at sites of injury or damage through the secretion of paracrine factors in vitro & in vivo. For example, our studies [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Nicole Hess
Oral Presentation
Nicole Hess, University of New England, Australia

Pathological changes to the cerebral microvasculature precede and/or accompany vascular disorders such as hypertension, neurovascular disorders such as AD, and cognitive decline.Individuals with a history of vascular risk factors (VRF’s) and vascular disease are considered [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Udai Pandey
Oral Presentation
Udai Pandey, University of Pittsburgh Medical Center, United States

Amyotrophic lateral Sclerosis (ALS) is a debilitating disease involving the progressive loss of motor functions resulting in neuronal death. Recently, several genes have found the mutated in ALS and majority of these ALS-causative gene are involved in regulating RNA metabolism. F [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Gabriele Saretzki
Oral Presentation
Gabriele Saretzki, Newcastle University, United Kingdom

I will give an overview about the enzyme telomerase and the non-canonical functions of the protein part TERT (Telomerase reverse transcriptase) with an emphasis of its beneficial effect within mitochondria which has been mainly analysed in cultured cell models in vitro. I will th [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Shinji Ohara
Oral Presentation
Shinji Ohara, Matsumoto Medical Center, Japan

Objective: Familial ALS with a mutation in the superoxide dismutase (SOD1) gene often shows marked intrafamilial phenotypic variation, although its pathologic background remains to be investigated. Methods: Immunohistochemical studies were performed on postmortem brain and spi [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Cristine Alves da Costa
Oral Presentation
Cristine Alves da Costa, Institut de Pharmacologie Moléculaire et Cellulaire, France

PD is a complex age-associated neurodegenerative disorder characterized by a progressive loss of midbrain dopamine neurons in the substantia nigra. Although, mainly of sporadic origin, the identification and characterization of PDassociated gene products, strongly contributed to [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Leonardo Pignataro
Oral Presentation
Leonardo Pignataro, Columbia University-City University of New York-CSI, United States

Chronic alcohol drinking causes profound physiological adaptations, which lead to physical dependence and tolerance. Some of these adaptations result from a complex chain of events that occur in the brain, long before a state of alcohol dependence is reached. Studies performed in [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Sabine Cordes
Oral Presentation
Sabine Cordes, Lunenfeld-Tanenbaum Research Institute/Mt Sinai Hospital, Canada

A key challenge in understanding and ultimately treating autism is to identify common molecular mechanisms underlying this genetically heterogeneous disorder. Transcriptomic profiling of autistic brains has revealed correlated misregulation of the neuronal splicing regulator nSR1 [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Jeffrey Liddell
Oral Presentation
Jeffrey Liddell, University of Melbourne, Australia

Copper is essential for normal brain function, but must be strictly regulated as either too much or too little copper leads to dysfunction. This is evident in many neurodegenerative diseases, most obviously in Wilson’s disease and Menkes disease driven by copper overload an [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Niall Finnerty
Oral Presentation
Niall Finnerty, Maynooth University, Ireland

In vivo amperometry is an electroanalytical technique whereby a sensitive and selective microelectrochemical sensor is implanted into a particular brain region for continuous real-time recordings of a particular neurochemical. A suitable potential is applied to the sensor surface [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Debashis Mukhopadhyay
Oral Presentation
Debashis Mukhopadhyay, Saha Institute of Nuclear Physics, India

Alzheimer’s Disease (AD) and Type 2 Diabetes (T2D), two serious health problems with vastly different symptoms, share a complex and linked mechanism. The majority of the data suggests that diabetics, specifically T2D subjects, are at much higher risk of developing AD than n [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Gilles Guillemin
Oral Presentation
Gilles Guillemin, Macquarie University, Australia

The kynurenine pathway (KP) of tryptophan metabolism is one of the major regulatory mechanisms of the immune response. Activation of the KP is implicated in the pathogenesis of a wide range of neuro inflammatory diseases. Several pro-inflammatory mediators can activate indoleamin [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Abigail Taky
Oral Presentation
Abigail Taky, University of Brighton, United Kingdom

Foetal alcohol syndrome (FAS) is a condition that currently affects approximately 1% of babies born in Europe and North America. It is characterised by memory impairment, developmental delay and distinctive facial features. This research uses a Mouse Prenatal Alcohol Exposure (PA [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Giuseppe Scalabrino
Keynote Presentation
Giuseppe Scalabrino, University of Milan, Italy

Cobalamin (Cbl), epidermal growth factor (EGF), and normal prions (PrPCs) are key molecules for myelin maintenance in the central (CNS) and peripheral nervous system (PNS). We have previously shown that Cbl deficiency causes an imbalance in some cytokines (e.g. tumour necrosis fa [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Harry W.M. Steinbusch
Keynote Presentation
Harry W.M. Steinbusch, Maastricht University, Netherlands

Despite the fundamental role of the brainstem in regulating vital functional abilities such as arousal, breathing, autonomic nervous system activity as well as regulating all higher cerebral functions via neurotransmitter projections systems originating in the brainstem, the role [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Pankaj Sharma
Keynote Presentation
Pankaj Sharma, University of London, United Kingdom

Stroke is the third commonest cause of death in the West yet by the year 2050 the WHO predicts that 80% of its occurrence will lay between India and China. These two most globally populous nations are home to an aging people with increasing risk factors for all cardiovascular dis [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Medvedev Svyatoslav
Oral Presentation
Medvedev Svyatoslav, N.P.Bechtereva Institute of the Human Brain of the Russian Academy of Sciences, Russian Federation

Analysis of clinical neurological and radiological data (MRI and FDG-PET) of patients with disorders of consciousness after coma (vegetative state, minimal consciousness state), obtained during the course of their treatment, has shown that a more prominent improvement of consciou [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Martin L. Pall
Oral Presentation
Martin L. Pall, Washington State University, United States

Non-thermal microwave/lower frequency electromagnetic fields (EMFs) act via voltage-gated calcium channel (VGCC) activation. Calcium channel blockers block EMF effects and several types of additional evidence confirm this mechanism. Low intensity microwave EMFs have been proposed [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Sergio Chief
Oral Presentation
Sergio Chief, Second University of Naples, Italy

Two functionally specialized cortical pathways of visual processing have been hypothesized: a dorsal (occipito-parietal) action-related and a ventral (occipito-temporal) perception-related pathway (Milner and Goodale, 1993, 2008). However, the ventral pathway would also contribut [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Laura Calza
Oral Presentation
Laura Calza, University of Bologna, Italy

Due to increased life expectancy, the prevalence of cognitive decline related to neurodegenerative diseases and to non-neurological conditions is increasing in western countries. Thus, there is an increasing demand, from both social and healthcare systems, for instruments and str [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Andrzej Pilc
Oral Presentation
Andrzej Pilc, Polish Academy of Sciences, Poland

The aim of our studies was to further investigate to antipsychotic potential of glutamate metabotropic receptor 4 (mGlu4) agonists and positive allosteric modulators (PAMs) as well as to investigate the interactions between mGlu4 receptor stimulators and 5-HT1A serotonin agonists [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Razvana Stanciu
Oral Presentation
Razvana Stanciu, Universite Libre de Bruxelles (ULB), Belgium

Background: Since the publication of the Diagnostic and Statistical Manual of mental disorders: DSM-5, sensory processing anomalies have for the first time been identified as diagnostic criteria in the international classification and thus been recognized as part of the core symp [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Kathryn Commons
Oral Presentation
Kathryn Commons, Children’s Hospital Boston-Harvard Medical School, United States

Serotonin neurotransmission has pervasive effects on behavior. While it is not responsible for any single behavior, serotonin helps shift between myriad of different behavioral repertoires and mood is perhaps related to our subjective experience of this shifting. It’s unkno [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Caroline Lucke
Oral Presentation
Caroline Lucke, Medical Campus University of Oldenburg, Germany

Cyclin-dependent kinase 5 (CDK5) is a multifunctional enzyme that plays numerous roles, notably in brain development. CDK5 is activated through its association with the specific activators, p35 and p39. Proteolytic procession of the N-terminal part of its activators has been link [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Sabrina Wang
Oral Presentation
Sabrina Wang, National Yang-Ming University, Taiwan

Orexins (also known as hypocretins) are two excitatory neuropeptides, including orexin-A (OX-A) and orexin B (OXB), produced by a small population of neurons located in the lateral hypothalamus, the dorsomedial hypothalamus, and the perifornical hypothalamus. The orexin neurons h [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Marta Nieto
Oral Presentation
Marta Nieto, Spanish National Research Council, Spain

Neuronal subtype specific transcription factors (TF) instruct key features of neuronal function and connectivity. Activity-dependent mechanisms also contribute to wiring and circuit assembly, but whether and how they relate to TF-directed neuronal differentiation is poorly invest [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Viviane Rostirola Elsner
Oral Presentation
Viviane Rostirola Elsner, IPA Methodist University, Brazil

Approximately 1% of the world’s population is affected by schizophrenia (SZ). Among possible factors, an imbalance on epigenetic machinery and inflammatory markers have been recognized in it´s physiopathogenesis and course. The patients with SZ usually adopts a sedent [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - K.L. Leenders
Oral Presentation
K.L. Leenders, University of Groningen, Netherlands

Objective: Idiopathic rapid eye movement sleep behavior disorder (iRBD) is a well-known risk factor for Parkinson’s disease, and provides an opportunity to test biomarkers in the prodromal stage. Recently, expression of the Parkinson’s disease related metabolic patter [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Leah K. Light
Oral Presentation
Leah K. Light, Brainchild Institute, United States

Dr. Leah Light, on behalf of the Svetlana Masgutova Educational Institute (SMEI), will discuss primary reflexes, which encompass our innate and subcortical, genetic motor intelligence that ultimately gives rise to more controlled physical activity, emotional and behavioral self-r [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Robyn Tolhurst
Oral Presentation
Robyn Tolhurst, Red Fern Communication, Australia

This presentation will cover tried and tested techniques for writing and publishing scientific papers including: The scientists’ toolkit Elements of writing a good paper Tips for overcoming writers’ block Getting published – what editors look for in [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Kenneth Gaines
Oral Presentation
Kenneth Gaines, Vanderbilt university Medical Center, United States

As the 5th leading cause of death and adult disability in the United States (US), stroke care is complex, involving multiple mechanisms and high risk and cost.Even when initial acute events are managed successfully, patient risk remains high from complications and poor risk facto [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Bruno Gonzalez
Oral Presentation
Bruno Gonzalez, Inserm - U1245 Team NeoVasc, France

I n neonates, excitotoxicity is a major process involved in hypoxic-ischemic brain lesions, and several studies reported neuroprotective effects of NMDA antagonists. However, there is more and more evidence indicating that, in the developing brain, glutamate exerts trophic effect [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Raquel Sofia Marques Neves
Oral Presentation
Raquel Sofia Marques Neves, Amana Healthcare Medical and Rehabilitation Hospital, United Arab Emirates

Globally, life expectancy from birth increased from 61.7 years in 1980 to 71.8 years in 2015 (GBD, 2015). This means we live longer and we are more susceptible to acute and/or chronic disease. Ischaemic hearth disease and stroke are the leading two cases of premature death and ac [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Marina Vladimirovna Zueva
Oral Presentation
Marina Vladimirovna Zueva, Moscow Helmholtz Research Institute of Eye Diseases, Russian Federation

The theory of ‘Fractality of sensations’ implies that the deficit of nonlinear complexity of the environment naturally leads to abnormal development and aging of the brain (Zueva M.V., 2015). The theory explains the need to restore the complex dynamics of the function [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Laehyun Kim
Oral Presentation
Laehyun Kim, Korea Institute of Science and Technology, Korea, Republic of

Stroke is the leading cause of adult neurological disabilities in most countries and typically damages particular regions of a patient’s brain and results in functional impairments. The process underlying the recovery of impaired motor functions after stroke involves brain [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Prokopenko Semen
Oral Presentation
Prokopenko Semen, Krasnoyarsk State Medical University, Russian Federation

Introduction: The first in Russia computer complex of neuropsychological programs for cognitive rehabilitation was developed at the department of Neurology and medical rehabilitation of Krasnoyarsk State Medical University. It consists of some computer programs modules that are f [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Luyang Tao
Oral Presentation
Luyang Tao, Soochow University, China

The talk is to update the current state of knowledge in post-TBI pathophysiological mechanisms, mainly including programmed cell death mechanisms; mechanism-based preclinical pharmacological intervention used in animal models; to summarize their effects on cell death, inflammator [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Anna Bezdeneznykh
Oral Presentation
Anna Bezdeneznykh, Krasnoyarsk State Medical University, Russian Federation

Introduction: Bilingualism is an important issue in neuropsychological assessment worldwide and especially in Russia. Republic of Tyva is federal subject of Russia, where ethnic Tuvans speak both languages Russian and Tuvan. The aim is post stroke cognitive assessment of Tyva res [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - M.R. Graham
Oral Presentation
M.R. Graham, Llantarnam Health Care, United Kingdom

Traumatic brain injuries (TBI) can be caused by a blow to the head, or sudden motions of the head, as in semi-contact or full contact sport and can result in death. The pathophysiology of TBI varies considerably depending on the location of the injury, within the brain and its se [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Serhiy Forostyak
Oral Presentation
Serhiy Forostyak, Charles University, Czech Republic

Diseases of the central nervous system (CNS) still remain among the most challenging pathologies known to mankind, having limited therapeutic possibilities and a very pessimistic prognosis. Stem cells technologies has passed a long and exciting way from the discovery, to preclini [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Gladstone C McDowell
Oral Presentation
Gladstone C McDowell, Integrated Pain Solutions, United States

Arachnoiditis-associated pain is notoriously treatment-resistant and may persist for many years. Despite treatment with varying combinations of drugs, patients are often left with a high pain burden. Many analgesics and medications used to treat such pain are contraindicated for [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Saema Ansar
Oral Presentation
Saema Ansar, Lund University, Sweden

Each year 15 million people suffer from a stroke and it is the number one cause of disability worldwide and a major drain on health cost. The only available FDA-approved drug therapy for ischemic stroke today is tissue plasminogen activator (t-PA), which is used to dissolve the o [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Barbara R. Cardoso
Oral Presentation
Barbara R. Cardoso, University of Sao Paulo, Brazil

Oxidative stress has a central role in the pathogenesis of neurodegeneration. Thus deficient status of antioxidants is associated with cognitive decline and risk of dementia. Here, we show the association between selenium status in two different populations (Australian and Brazil [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Hassan Ravari
Oral Presentation
Hassan Ravari, Mashhad university of medical sciences, Iran (Islamic Republic of)

Early intervention within 2 weeks of symptom onset has been advocated and become standard of care for most patients with transient ischemic attacks. The optimal timing of carotid endarterectomy after a recent ischemic stroke is a subject of controversy because of a presumed high [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Maria P. Mcgee
Poster Presentation
Maria P. Mcgee, Wake Forest University Medical School, United States

Aging is associated with gradual and variable changes of some cognitive functions in humans and animals but the causes of these changes and their individual variability remain unclear. Similarly, hydration is variable among individuals and the proportion of brain weight relative [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Antje Anji
Poster Presentation
Antje Anji, Kansas State University, United States

The heterodimeric enzyme a-glucosidase II (GII), an important enzyme in chaperone-assisted folding of nascent glycoproteins in the rough endoplasmic reticulum (RER) is comprised of a beta subunit (GIIb) and the catalytic alpha subunit (GIIa). The soluble GIIa is retained in the R [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Guy Massicotte
Poster Presentation
Guy Massicotte, Trois-Rivières University, Canada

Background: Tau proteins are known to help maintaining the structure of a neuron, including tiny tube-like structures called microtubules, which deliver nutrients throughout cells. However, when hyperphosphorylated, these proteins can become toxic for neurons by forming tangles i [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Weller Alexandra
Poster Presentation
Weller Alexandra, Carribbean Medical University School of Medicine, Netherlands

Introduction: True hyperosmia in a patient with phantosmia has not heretofore been described. Case study: A 19-year-old right –handed female presented with a 4-month history of sudden onset of hallucinated smell and taste after swimming, when water infused her nostrils. [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Maria Kondrat-Wrobel
Poster Presentation
Maria Kondrat-Wrobel, Medical University of Lublin, Poland

The aim of this study was to evaluate the influence of arachidonyl-2’-chloroethylamide (ACEA – a potent and selective cannabinoid CB1 receptor agonist) on the anticonvulsant properties of six selected antiepileptic drugs (i.e., clobazam, lacosamide, levetiracetam, phe [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Caroline Reid
Poster Presentation
Caroline Reid, Maynooth University, Ireland

This presentation details the in vivo characterisation of microamperometric sensors for the real-time monitoring of nitric oxide (NO), oxygen (O2) and hydrogen peroxide (H2O2) in the brain extracellular fluid of immunocompromised NOD SCID mice. Highly selective and sensitive NO, [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Korotkov Alexander
Poster Presentation
Korotkov Alexander, N.P.Bechtereva Institute of the Human Brain of the Russian Academy of Sciences, Russian Federation

Monitoring of patients with disorders of consciousness after coma with 18F FDG positron emission tomography (18F-FDG PET) revealed an improvement of consciousness and behavioral signs of awareness, as well as increases of regional metabolic activity after correction of generalize [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Vainshenker Yulia
Poster Presentation
Vainshenker Yulia, N.P.Bechtereva Institute of the Human Brain of the Russian Academy of Sciences, Russian Federation

Introduction and Objectives: Previously we found that botulinum toxin therapy of generalized spasticity in patients with disorders of consciousness after coma improves the functional state of the brain and consciousness. However, when do these central changes start and how they d [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Agnieszka Lukomska
Poster Presentation
Agnieszka Lukomska, Pomeranian Medical University, Poland

Fluorine is a strong neurotoxin which can decrease the intelligence quotient and cause problems with learning and concentration. The Extracellular Matrix (ECM) of the central nervous system serves as the environment for neurons and glial cells, and at the same time, it plays the [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Karolina Dec
Poster Presentation
Karolina Dec, Pomeranian Medical University, Poland

Long term exposure to fluorine in pre and neonatal period is dangerous because this element is able to penetrate through the placenta and to cross the blood-brain barrier. Young individuals are less resistant to the toxic influence of fluorine due to the fact that their defensive [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Katarzyna Zaluska
Poster Presentation
Katarzyna Zaluska, Medical University of ublin, Poland

The purpose of this study was to evaluate the effect of dronedarone (a multi-channel blocker inhibiting outward potassium currents, inward rapid sodium current and L-type calcium channels) on the anticonvulsant properties of some selected antiepileptic drugs (i.e., carbamazepine, [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Takashi Koizumi
Poster Presentation
Takashi Koizumi, Kyoto Prefectural University of Medicine, Japan

The preclinical diagnosis of hypertensive cerebral vascular dementia (CVD) is important in an aging society. Cerebral white matter lesions (CWMLs) accompanied by hypertension are often visualized by magnetic resonance imaging (MRI) in the early stage, but after the onset of cogni [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Shang-Hsun Yang
Poster Presentation
Shang-Hsun Yang, National Cheng Kung University College of Medicine, Taiwan

MicroRNAs (miRNAs) play important roles in several neurobiological processes, including the development and progression of diseases. Previously, we identified that one specific miRNA, miR-196a, provides neuroprotective effects on Huntington’s disease (HD), although the deta [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Yuanyuan Wu
Poster Presentation
Yuanyuan Wu, Zhejiang Chinese Medical University, China

Part 1: Electro-acupincture influence inflammation induced pain memory via cAMP/PKA/CREB pathway in the Anterior Cingulate Cortex. Our precious studies demonstrate that inflammation indused pai memory can be indeed caused by reapeated injections in rats. EA stimulation could i [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - ANWAR SATEF
Poster Presentation
ANWAR SATEF, University of hassan 1 SETTAT, Morocco

Alteration of GABAergique neurotransmission in the central nervous systeme is involved in the generation of neuronal hyperexitability and seizures. GABAergique transmission blocked by GABA antagonists injected i.p. intracerebrally induce seizures. In the present study, we charact [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Maria Kondrat-Wrobel
Poster Presentation
Maria Kondrat-Wrobel, Medical University of Lublin, Poland

The aim of this study was to evaluate the influence of arachidonyl-2’-chloroethylamide (ACEA – a potent and selective cannabinoid CB1 receptor agonist) on the anticonvulsant properties of six selected antiepileptic drugs (i.e., clobazam, lacosamide, levetiracetam, phe [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Viviane Rostirola Elsner
Poster Presentation
Viviane Rostirola Elsner, IPA Methodist University, Brazil

Emerging evidences have been pointed out that the imbalance on epigenetic machinery exert a pivotal role in the physiopathology of several neurological, neurodegenerative and neuropsychiatric conditions. However, this relationship in spinal cord injury (SCI) have been poorly inve [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Gladstone C McDowell
Poster Presentation
Gladstone C McDowell, Integrated Pain Solutions, United States

Introduction: The Patient Registry of Intrathecal Ziconotide Management (PRIZM) evaluates effectiveness and safety of intrathecal (IT) ziconotide. Methods: PRIZM is an open-label, long-term, multicenter (23 sites), observational study of adult patients with severe chronic pain [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Jihye Park
Poster Presentation
Jihye Park, Seoul St.Mary Hospital, Korea, Republic of

Objectives: To present the outcomes of 191 cases treated surgically for intracranial aneurysmal who underwent intraoperative SSEP and MEP monitoring and to analyze the sensitivity, specificity and predictive value of changes in predicting postoperative stroke. for intracranial an [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Naserddine Hamadi
Poster Presentation
Naserddine Hamadi, United Arab Emirates University, United Arab Emirates

Bilateral adrenalectomy (ADX) has been shown to damage the hippocampal neurons. However, the effects of shortterm ADX is not studied. Therefore, we aimed to investigate the effects of short-term ADX on the levels of proinflammatory cytokines, response of microglia, astrocytes, ne [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - MARIA DIANA LORENA RUBIO NAVARRO
Poster Presentation
MARIA DIANA LORENA RUBIO NAVARRO, Universidad Nacional Autonoma de Mexico, Mexico

Gestational and lactating period is a time of rapid development for the mammals. The effects of restriction of nutrients in these periods produce alterations in fetal neurogenesis, morphogenesis, synaptogenesis; and during the lactating period interferes migration, synaptogenesis [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - KHIN MAUNG BO
Poster Presentation
KHIN MAUNG BO, Northern Lincolnshire and Goole NHS Foundation Trust, United Kingdom

Background: Basal Ganglion Neuronal Network (BGNN) dysfunction in Parkinson’s disease (PD)is a complex one to explain Cardinal Signs (CS) satisfactorily. CS of PD are: Tremor, Rigidity, Bradykinesia and Postural Instability (PI). Objective: To propose ad [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Mira Rakacolli-Kapisyzi
Keynote Presentation
Mira Rakacolli-Kapisyzi, President of Albanian Society of Neurology, Albania

Introduction: Presently, there is limited information on stroke care in the very old (80 years and older). Aim: To evaluate vascular risk factors, stroke subtypes and clinical outcomes in very old patients admitted at our hospital with acute stroke. Methods: We included in [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Henry Bakunts
Keynote Presentation
Henry Bakunts, International Medical Centre “”STROKE””, Armenia

At present, due to introduction of highly informative instrumental methods of assessment of cerebral blood flow state, microcirculation system and brain tissue metabolism diagnosis or vascular diseases of the brain is significantly improved. This brought to reassessment of existe [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Lars Hakan Thorell
Oral Presentation
Lars Hakan Thorell, Linkoping University, Sweden

The very strong relationship between electrodermal hyporeactivity and suicide and other suicidal behaviors in depressed patients (Edman et al., 1986; Thorell, 1987, 2009; Eriksson et al., 2008; Thorell et al., 2013, 2014; Sarchiapone et al., 2017, 2017 (not published yet); Sarchi [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Martin Egerth
Oral Presentation
Martin Egerth, Lufthansa Aviation Training GmbH, Germany

Between 300 and 500 people die every year in plane crashes worldwide. Despite this seemingly high number, the number of preventable deaths annually as a result of medical errors is far greater. Patients die daily due to human errors committed by doctors, nurses and hospital staff [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Munzberg Mathias
Oral Presentation
Munzberg Mathias, BG Klinik Ludwigshafen, Germany

Between 300 and 500 people die every year in plane crashes worldwide. Despite this seemingly high number, the number of preventable deaths annually as a result of medical errors is far greater. Patients die daily due to human errors committed by doctors, nurses and hospital staff [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Cecilia Montanez
Oral Presentation
Cecilia Montanez, Centro de Investigacion y de Estudios Avanzados del IPN, Mexico

Cognitive impairment and retinal abnormalities have been reported in the X-linked Duchenne muscular dystrophy. The intellectual disabilities are associated with mutations in the shortest dystrophins Dp71 and Dp40. Molecular, cellular, physiological and behavioral alterations are [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Moataz Mohamed Talaat Mohamed Kamel El Semary
Oral Presentation
Moataz Mohamed Talaat Mohamed Kamel El Semary, Cairo university, Egypt

To evaluate efficacy of biofeedback training on treatment of bladder and erectile dysfunction in paraplegic patients. Methods: Thirty male paraplegic patients within 6 to 18 months after injury, ages ranged from 20 to 35 years, participated in this study for a treatment period of [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Maria-Magdalena Georgescu
Oral Presentation
Maria-Magdalena Georgescu, Louisiana State University, United States

Smooth muscle cell (SMC) contractility is essential for the function of vessels and viscera and relies on the integrity of the actin-myosin apparatus. Two tissue-specific actin isoforms, α2-smooth muscle actin (SMA), encoded by the ACTA2 gene, and α-SMA are predominan [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Teruna J. Siahaan
Oral Presentation
Teruna J. Siahaan, The University of Kansas, United States

One of the major challenges in studying brain function and diseaseslies in the difficulty in deliveringmoleculesto the brain due to the presence of the blood-brain barrier (BBB). This project is aimed at developing a novel and effective method to deliver molecules to the brain fo [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Toshiki Mizuno
Oral Presentation
Toshiki Mizuno, Kyoto Prefectural University of Medicine, Japan

Hereditary Cerebral Small Vessel Disease (CSVD) can be divided into three types. autosomal dominant, autosomal recessive and X-linked. While CADASIL is most common in autosomal dominant type, CARASIL is the only one recessive type. CADASIL and CARASIL have a couple of similar cha [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Katherine L Wisner
Oral Presentation
Katherine L Wisner, Northwestern University, United States

During pregnancy, the activities of Cytochrome (CYP) P450 enzymes are altered. However, minimal information is available to inform dosing guidelines. My team has published data demonstrating that the plasma concentrations of sertraline, fluoxetine, citalopram and escitalopram dec [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Meena Kumari
Oral Presentation
Meena Kumari, Kansas State University, United States

The N-methyl-D-aspartate (NMDA) receptors are important in neuronal development, synaptic plasticity, long-term potentiation, and neuronal cell death. NMDA receptors consisting of NR1 and NR2B subunits are a target of alcohol and are believed to play a role in the development, at [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Magnus Gram
Oral Presentation
Magnus Gram, Lund University, Sweden

Rapid development in neonatal and cardiac surgery care in newborns has enabled survival of an increasing number of infants following preterm birth and of infants with congenital heart defects. Unfortunately this is accompanied by a significant prevalence of neurological and cogni [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Joanna Czarzasta
Oral Presentation
Joanna Czarzasta, University of Warmia and Mazury, Poland

Neuroinflammation is a major player in the course of amyotrophic lateral sclerosis (ALS), and is characterized by astrocyte and microglial activation, T cell infiltration and the overproduction of proinflammatory factors. Among many components/molecules engaged in the inflammator [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Dennis J. Dlugos
Oral Presentation
Dennis J. Dlugos, University of Pennsylvania School of Medicine, United States

Epilepsy of infancy with migrating focal seizures (EIMFS) is a severe infant-onset epileptic encephalopathy, often caused by mutations in the KCNT1 gene, and standard treatments are ineffective.The cardiac anti-arrhythmic drug quinidine is a partial antagonist of KCNT1, making it [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Lynda El-Hassar
Oral Presentation
Lynda El-Hassar, Yale School of Medicine, United States

Fragile X syndrome (FXS) is the most common form of inherited intellectual disability. In common with autism, FXS is characterized by hypersensitivity to many types of sensory stimuli, including environmental sounds. Our previous work has shown that mice lacking the gene for FMRP [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Hoi Ki Kate Lui
Oral Presentation
Hoi Ki Kate Lui, Tseung Kwan O Hospital, Hong Kong

Theclinical characteristics of Chinese adults patients presenting with status epilepticus to intensive care units were be discussed. A retrospective review was performed on patients admitting to the intensive care units with status epilepticus ( SE ) over a 11-year period from 20 [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Shuhei Yamaguchi
Oral Presentation
Shuhei Yamaguchi, Shimane University, Japan

Aging is associated with deterioration in a number of cognitive functions. Many studies have demonstrated the beneficial effect of physical fitness on cognitive function, especially executive function. The graph theoretical approach models the brain as a complex network represent [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Victor Vvedensky
Oral Presentation
Victor Vvedensky, Kurchatov Inststute, Russian Federation

High spatial selectivity of multichannel SQUID-magnetometers (MEG) provides opportunity to distinguish contributions of different cortical electric sources into magnetic signals measured around the head. One can extract activity of a single source with specific behavior, when man [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Michael Luedtke
Oral Presentation
Michael Luedtke, Johnson & Johnson, United States

I nternational medical device development and proper design control methods require formative and summative validation studies. In the past, some company usability studies were conducted with employees and submitted for Regulatory clearance for Medical Devices. Recently, FDA has [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Fatimah Alqarni
Oral Presentation
Fatimah Alqarni, King Abdullah bin Abdulaziz University hospital, Saudi Arabia

Pompe disease is a rare autosomal recessive disorder caused by a deficiency of the lysosomal enzyme alpha-glucosidase. Late-onset Pompe disease has a complex multisystem phenotype characterized by arange of symptoms which has led to underestimate the disease among adult populatio [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Bilgehan Atilgan ACAR
Oral Presentation
Bilgehan Atilgan ACAR, Sakarya University Faculty of Medicine, Turkey

Objectives: Patients with primary restless legs syndrome (pRLS) often have signs or symptoms of autonomic failure, including cardiovascular system. Gastrointestinal, sudomotor, thermoregulation, and bladder abnormalities are often reported in Restless Legs Syndrome but there is l [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Albekov Nurvadi
Oral Presentation
Albekov Nurvadi, Chechen State University, Russian Federation

The article discusses the hypothesis of possibility of determining the fuzzy linguistic sets of communicative situation based on field of emergence. It is assumed that on the base of a communicative situation there caused a field of emergence, which denotes the boundary of struct [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Paul Chapple
Oral Presentation
Paul Chapple, Queen Mary University of London, United Kingdom

Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) is a childhood-onset neurological disease, with pyramidal spasticity and cerebellar ataxia. ARSACS results from mutations in the SACS gene that encodes sacsin, a modular protein with conserved domains that indicat [....] » Read More

Speaker at International Conference on Neurology and Brain Disorders 2017 - Turkan ACAR
Oral Presentation
Turkan ACAR, Sakarya University Faculty of Medicine, Turkey

Objectives: Medication overuse headache (MOH) is a type of chronic headache disorder caused by excessive use of acute medications and a public health problem with a worldwide prevalence of 1–2%. Each medication class has a specific threshold. In this study we wanted to demo [....] » Read More

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