Title : Neuroprotective agents target molecular mechanisms of programmed cell death after traumatic brain injury
Abstract:
The talk is to update the current state of knowledge in post-TBI pathophysiological mechanisms, mainly including programmed cell death mechanisms; mechanism-based preclinical pharmacological intervention used in animal models; to summarize their effects on cell death, inflammatory events, and prolonged motor and cognitive deficits; and further evaluate their potential success for clinical application. Many of the above mentioned mechanisms that may be important targets for limiting the consequences of TBI.
Audience take away:
- Post-TBI pathophysiological mechanisms;
- Mechanism-based preclinical pharmacological intervention used in animal models;
- Summarize the effects of the agents on cell death, inflammatory events, and prolonged motor and cognitive deficits; and further evaluate their potential success for clinical application.
