Did the patient genetically inherit their complex psychophysical pathological condition/s or are they simply adopting and/or mirroring other members of their family who have the complex psychophysical condition that the patient is exhibiting? Over several decades it has been f [....] » Read More
Recovery from brain trauma is in part dependent upon the brain’s ability to adapt to new and challenging experiences. The brain’s capacity to structurally and functionally reorganize nerve cells and spontaneously develop new neuronal networks defines neuroplasti [....] » Read More
In this talk I first review several different notions of the “unity of consciousness” such as subject unity, object unity, spatial unity, and perhaps most common “phenomenal unity” which is the general notion that, from the first-person point of view, we e [....] » Read More
Traumatic spinal cord injuries (TSCI) are life-changing events from medical, physical, psychological, social, financial, vocational, environmental & matrimonial effects. The combination of consequent generalised physiological impairment, multi-system malfunction, multiple dis [....] » Read More
Olfactory loss is a key symptom in the prodromal and early stages of Parkinson’s disease. Noninvasive imaging biomarkers can provide a powerful tool for diagnosing the diseases, monitoring the progression, and evaluating potential therapeutics. In this talk, I will first de [....] » Read More
Subarachnoid Hemorrhage (SAH) continues to be a leading cause of morbidity and mortality, with cerebral vasospasm as a common etiology of worse clinical progression. The purpose of this study was to evaluate and review the current literature concerning the effective treatment of [....] » Read More
Von Willebrand factor (VWF) is a multimeric protein that mediates thromboinflammation and has been linked to traumatic brain injury (TBI), specifically in the pathogenesis of early brain injury. Activated endothelium secretes VWF multimers as long hyperadhesive strings. During TB [....] » Read More
Background: There is an expanding body of literature implicating heart disease and stroke as a risk factor for Alzheimer disease (AD), highlighting significant pathways. Hawaii state has the most diverse ethnic population in the US and there exists significant racial health dis [....] » Read More
In temporal lobe epilepsy, the ability of the dentate gyrus to limit excitatory cortical input to the hippocampus breaks down, leading to seizures. The dentate gyrus is also thought to help discriminate between similar memories by performing pattern separation, but whether epilep [....] » Read More
Creutzfeldt–Jakob disease (CJD) is a rare form of rapidly progressive, neurodegenerative disease that results from the misfolding and accumulation of an aberrant, disease-associated prion protein (PrPD). CJD affects 1–1.5 cases per million per year with the sporadic-t [....] » Read More
Traumatic brain injury (TBI) is one of the leading causes of death and disability globally and results in an array of deficits that can be extremely difficult to diagnose and treat due to their heterogeneity. Individuals with TBI often live with permanent emotional, physical, and [....] » Read More
Background: Parkinson´s Disease (PD) is a progressive neurodegenerative disease manifesting itself in motor and nonmotor symptoms. With disease progression, cognitive deficits ranging from mild cognitive impairment (MCI) to dementia (Galtier et al., 2016) as well as [....] » Read More
Endovascular coiling (EC) has been identified in systematic reviews and meta-analyses to produce more favourable clinical outcomes in comparison to neurosurgical clipping (NC) when surgically treating a subarachnoid haemorrhage from a ruptured aneurysm. Cost-effectiveness analyse [....] » Read More
Introduction: The COVID-19 pandemic has had a significant impact on healthcare systems all over the world. Concerns have been expressed regarding the potential for diagnostic and therapeutic delays in diseases such as cancer because of this. The delays in hospital admissions and [....] » Read More
Charcot-Marie-Tooth (CMT) disorder is a hereditary neurological condition characterized by progressive muscle weakness, sensory loss, and motor dysfunction. Current treatment op:ons primarily focus on managing symptoms and improving quality of life. However, unprecedented results [....] » Read More
Ziconotide is a synthetic, water-soluble cone snail venom-derived peptide with a molecular weight of 2,639 Daltons. It is a nonopioid analgesic that selectively binds to N-type voltage-sensitive calcium channels on primary nociceptive afferent nerves in the dorsal horn of the spi [....] » Read More
The human body tumour lesions are almost ordinary events in its life. Almost every people has moles. The moles are in fact small tumours, which normally doesn’t grow but in certain condition, triggered say by mechanical or radioactive events may become to have an uncontroll [....] » Read More
Pain is one of the most frequent complaints of patients, being responsible for causing damage to the public health system, disability, and loss of functionality to patients. Understanding the different levels and types of Pain and its possible musculoskeletal dysfunctions is ess [....] » Read More
Traumatic brain injury (TBI) induced coma is a key factor in poor clinical prognosis and poses a significant burden to families and society. However, there is a lack of first-line wake-promoting therapies with proven efficacy and ultra-early intervention. Acupuncture has been cer [....] » Read More
Background: Depressive symptoms are common in Alzheimer's disease (AD) and are associated with cognitive function. Amygdala functional connectivity (FC) and radiomic features related to depression and cognition. However, studies have yet to explore the neural mec [....] » Read More
Alzheimer’s disease (AD) is a common neurodegenerative diseases and it is the leading cause of dementia. Due to AD's slow rate of progression, patients have the opportunity to receive early therapy through regular screenings. The available diagnostic techniques today su [....] » Read More
Epilepsy, a serious neurological disorder affecting a substantial global population, necessitates efficient and accurate diagnostic methods. The electroencephalogram (EEG) has been a pivotal tool in epilepsy detection due to its ability to capture brain activity during seizures. [....] » Read More
The human brain has developed different neural mechanisms to perceive time in twelve scales. Neural population clocks and ramping activity are the mechanisms responsible for perceiving subsecond timing, which includes speech recognition and internal discrimination. The human brai [....] » Read More
Introduction: Mild Traumatic Brain Injury (mTBI) or concussion is a common yet undermanaged and underreported condition. This systematic review and meta-analysis aim to determine the efficacy of Vestibular Rehabilitation Therapy (VRT) as a treatment option for mTBI. Methods: [....] » Read More
Central Post Stroke Pain (CPSP) is a form of chronic neuropathic pain presenting in 8-55% of patients within the first year after their first-stroke incident. The wide range of CPSP prevalence is due to the nature of CPSP onset and also lack of standardised diagnostic tool for CP [....] » Read More
Background: People with neglect suffer from various spatial deficits in several modalities, which in many cases impair everyday functioning. Virtual reality (VR) is a form of interaction between humans and computers in which a real or imaginary environment is simulated. Users in [....] » Read More
Background: Daytime sleepiness is defined as the uncontrollable drowsiness during daytime that can interfere with performing daily activities and psychomotor performance. Poor sleep quality and bad sleep behaviors have a large contribution to the prevalence of daytime sleepiness [....] » Read More
Background and Aims: To see the patients presented in the Emergency Department of SRD with headache as a symptom of COVID-19. Methods: We have seen frequency and characteristic of headache in 180 patients in an emergency with a test of polymerase chain reaction positive. [....] » Read More
Autism is a neuro-developmental spectrum disorder that is highly variable in each person and is caused by a brain development disorder, which occurs during infancy, then goes through a fixed period without recovery, and its symptoms continue until adulthood or in Some improve and [....] » Read More
Purpose: 4D perfusion magnetic resonance imaging (MRI) with intravenous injection of contrast agent allows for a radiation-free assessment of regional lung function. It is therefore a valu- able method to monitor response to treatment in patients with chronic obstructive pulmona [....] » Read More
Trigeminal neuralgia (TN) and hemifacial spasm (HFS) are two distinct debilitating neurological conditions that may occasionally coexist, posing diagnostic challenges and requiring comprehensive evaluation. Our study aims to present a case and conduct a literature review to explo [....] » Read More
Sporadic Creutzfeldt-Jakob Disease (CJD) is one of the diseases that should be considered in dementia-related processes seen between the ages of 50-70. It can be distinguished from other diseases with dementia with its clinical features, typical electroencephalography (EEG) findi [....] » Read More
Brain-Computer Interface (BCI) technology is a rapidly advancing aspect of the field of neuroscience. One particular use of BCI technology, multi-person brain-to-brain Interfaces (mBBI), is a rapidly growing field of study. To enable further development, we must first look toward [....] » Read More
Introduction: Hyponatraemia after subarachnoid haemorrhage (SAH) is common, however the incidence, and association of hyponatraemia with vasospasm, morbidity, and mortality, has yet to be defined. We aimed to identify incidence of hyponatraemia after SAH, and association with me [....] » Read More
A patient diagnosed with Ankylosing Spondylitis on long-term etanercept treatment presented in the Emergency Department with subacute progressive cognitive dysfunction and personality change. He further developed psychiatric symptoms, autonomic dysfunction and orofacial dyskinesi [....] » Read More
The current strategies to mitigate the toxicity of misfolded SOD1 in familial ALS via blocking SOD1 expression in the CNS are indiscriminative for misfolded and intact proteins, and as such, entail a risk of depriving CNS cells of their essential antioxidant potential. As an a [....] » Read More
Introduction: Infantile Neuronal Ceroid Lipofuscinosis (INCL, also known as CLN1 Batten Disease, or CLN1) is a rare, devastating neurodegenerative disease affecting infants and children. CLN1 is caused by mutations in the CLN1 gene, which encodes the enzyme palmitoyl-prote [....] » Read More
The standard of care for multiple sclerosis is to perform surveillance MRI to monitor disease activity, given that subclinical or ‘silent’ lesions can often occur. In two rare demyelinating diseases, neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendr [....] » Read More
Previous work in humanized mouse models of human immunodeficiency virus type-1 (HIV-1) has demonstrated that knocking down the matricellular protein Osteopontin (OPN) in vivo leads to a robust increase in the expression of proinflammatory markers TSPO and AIF-1, suggesting that O [....] » Read More
Alzheimer’s disease (AD) is a neurodegenerative disease that causes cognitive impairment, characterized by progressive cognitive decline, memory loss, and neuronal death in the cerebral cortex, hippocampus, and other brain regions. Hallmarks of its pathology are amyloid bet [....] » Read More
Introduction: Leucine-rich glioma-inactivated 1 (LGI1)-antibody encephalitis can be difficult to diagnose. It should be considered when there is clinical presentation of brief, unilateral jerking of the face and arm, termed faciobrachial dystonic seizures (FBDS), which is a hall [....] » Read More
Neuralgic amyotrophy, or Parsonage-Turner syndrome (PTS), is a rare autoimmune inflammatory disorder of the brachial plexus. Patients will present with episodes of extreme shoulder pain with eventual development of paresis and atrophy of the innervated muscle. These symptoms may [....] » Read More
Transverse myelitis is a rare but documented sequela of heroin use. While the underlying etiology is not clearly elucidated, the prevailing pathophysiologic mechanism amongst existing literature suggests an immune mediated hypersensitivity reaction due to heroin insufflation fo [....] » Read More
Summary/Objective: To describe a patient who developed refractory vestibular migraine after a motor vehicle accident (MVA) and COVID-19 infection with subsequent improvement while on multiple CGRP antagonists with off-label dosing and to provide support for the role of CGRP in v [....] » Read More
Parkinsonian disorders, including Parkinson's disease (PD), multiple system atrophy (MSA), dementia with Lewy bodies (DLB), progressive supranuclear palsy (PSP), and corticobasal syndrome (CBS), present shared early motor symptoms but differing cellular and regional pathophys [....] » Read More
Background: Parkinson’s disease (PD) is a chronic neurodegenerative disease affecting more than 10 million people worldwide. PD is commonly associated with motor symptoms like bradykinesia and non-motor symptoms like autonomic changes. Oftentimes, these symptoms can be rec [....] » Read More
Background: Traumatic Brain Injury (TBI) is an injury to the brain caused by a blow to the head, which is commonly seen in motor vehicle accidents, sports injuries, falls, and assaults. Studies have shown that emotional states such as agitation can result in a longe [....] » Read More
Glioblastoma (GBM) is a fatal brain cancer in adults with ineffective existing treatment methods. Cell adhesion molecules (CAMs) are proteins that are expressed on the surface of cells and enable them to communicate and interact with one another and the surrounding environment. I [....] » Read More
M80T mutation of triose phosphate isomerase (TPI) presents one potential contributory pathway for developing Alzheimer’s disease (AD). M80T effects the triose phosphate isomerase (TPI) enzyme activity within the glycolysis pathways producing enhanced levels of methylglyoxal [....] » Read More
Studies have shown differences in neuropsychiatric symptoms (NPSs) of Alzheimer’s disease?AD? between the males and females. However, we do not know whether this difference is influenced by disease severity. Method: Patients with AD who visited the Memory Cl [....] » Read More
Objective: Generalized anxiety disorder (GAD) is a typical multisystem disease characterized by decreased activity in the left dorsolateral prefrontal cortex (DLPFC). Transcranial near-infrared stimulation (tNIRS) was used to stimulate the left DLPFC to relieve anxiety, and tran [....] » Read More
Frontotemporal dementia (FTD) is the second most common form of presenile dementia; however, its diagnosis has been poorly investigated. Previous attempts to diagnose FTD using quantitative electroencephalography (qEEG) have yielded inconsistent results in both spectral and funct [....] » Read More
Introduction: We present a case of a 47-year-old female who had a painless soft mass on her scalp misdiagnosed as a trichilemmal cyst instead of dermatofibroma protuberans. Case Presentation: In January 2021, a woman presented to a clinic with a headache and swelling on the [....] » Read More
In humans, carotid stenosis of 70% and above might be the cause of clinical symptoms such as transient ischemic attack and stroke. No clinical or animal studies have evaluated mild carotid occlusion, and few examined unilateral occlusion. Here, Wistar rats underwent bilateral or [....] » Read More
Stroke is ranked as the second major cause of death and a major cause of disability in the world with increasing annual numbers. Ischemic stroke (IS) being the most prevalent form of stroke, the role of COVID-19 in the risk of complications and outcomes for patients with IS is st [....] » Read More
Cryptococcus neoformans infection predominantly occurs in the immunocompromised patients. However, it may infect apparently immunocompetent hosts and present as stroke mimic. We are reporting a case of elderly gentleman who presented with acute onset right upper limb weakness, at [....] » Read More
Encephalomyelitis treated with the ganglioside-containing drug were studied. To assess the clinical severity of the disease, lethality, body weight, neurological deficit, and morphological signs of experimental allergic encephalomyelitis disease were taken into account. The sever [....] » Read More
Multiple sclerosis (MS), a debilitating inflammatory disease of the central nervous system, afflicts approximately 2.5 million people worldwide. Manifesting through a variety of symptoms including gait and balance impairments, the progression of MS notably exacerbates balance dif [....] » Read More
Addiction can be defined as an irresistible desire for an object, individual or entity although it is known to be harmful to the person physically or psychologically. In addiction physical dependence is explained as changes in the brain structure as well as, neurochemistry as sub [....] » Read More
Alzheimer’s disease (AD) is the leading form of dementia worldwide, but its early detection and diagnosis remain a challenge. MicroRNAs (miRNAs) are a group of small endogenous RNA molecules that regulate mRNA expression. Recent evidence suggests miRNAs play an important ro [....] » Read More
Background: Tau-PET Scan measures brain tau deposition. Mini Mental Status Examination (MMSE) is used for cognitive impairment in (MCI) and Alzheimer Disease (AD). We analyzed the correlation of MMSE to tau-PET imaging in a memory clinic. Research Hypothesis: Tau-PET positiv [....] » Read More
Neurovascular coupling describes the signalling pathways between neurons, glia and vascular cells that ensure regional increases in brain activity are matched by corresponding increases in local blood flow. Increasing evidence suggests that these pathways are dysfunctional in Alz [....] » Read More
Introduction: Posterior reversible encephalopathy syndrome (PRES) is a rare neurological disorder that classically presents with sudden onset of visual disturbances, seizures, headaches, and altered mentation in the context of uncontrolled hypertension. The diagnosis of PRES can [....] » Read More
Complex Regional Pain Syndrome (CRPS) is a rare chronic neuropathic pain disorder with limited treatment modalities that can negatively impact a patient’s quality of life. This case describes a 58 year-old female who was diagnosed with CRPS following a difficult recovery fr [....] » Read More
Objectives: TSA raises awareness of CACNA1C-related disorders (CRD) including Timothy Syndrome (TS) and LongQT8 (LQT8) to improve diagnosis, treatment and coordination of care for individuals worldwide. Methods: Caregivers of individuals with CRD including TS and LQT8 comple [....] » Read More
Objectives This study aimed to compare the safety and efficacy of balloon and non-balloon (or dilator) gastrostomy devices in radiologically inserted gastrostomy for patients with neurological disease. Materials and Methods A retrospective analysis of 152 patients was conduc [....] » Read More
Alopecia intellectual disability syndromes 4 (APMR4) is a very rare autosomal recessive condition caused by a mutation in the LSS gene present on chromosome 21. This syndrome has a clinical heterogeneity mainly exhibited with variable degrees of intellectual disability (ID) [....] » Read More
Scoliosis is commonly described as a 3D spinal deformity resulting in a curvature of 10 degress or more with a rotational spin. All the bones in the body have three cells that work together for the proper growth of the bone: The osteocyte,cell that coordinates the osseous work [....] » Read More
The COVID-19 pandemic has caused an unprecedented impact on global health, affecting millions of people worldwide. In effect to tackling the devastating outcomes of the disease, the development of vaccines was the primary focus of health researchers worldwide. Thus, a few brands [....] » Read More
Background: Caffeine’s wakefulness-promoting and sleep-disrupting effects are well established, yet whether caffeine affects human circadian timing is unknown. Also, Evidence suggests evening-type individuals have a higher risk of reporting psychological distress. However, [....] » Read More
Introduction: Circadian rhythms are regulated by genetic and environmental components. The association of intrinsic and extrinsic factor modulates physiological and individual sleep schedules sleep hygiene and even different chronotype. Evidence suggests evening-type individuals [....] » Read More
Background: Caffeine is one of the most widely consumed stimulants in the world , caffeine is commonly consumed to help offset fatigue, however, it can have several negative effects on sleep quality. Also chronotype are known to have an association with sleep quality . less stu [....] » Read More
The neurological condition marked by memory loss and increasing cognitive deterioration is referred to as Alzheimer's disease (AD). Early and accurate detection of AD plays a crucial role in providing timely interventions and improving patient outcomes. In this thesis, we pro [....] » Read More
Stroke is a leading cause of morbidity and second cause of mortality worldwide. Early participation in rehabilitation treatments such as neurostimulant drugs showed to be beneficial. Amantadine usually used as Parkinson disease treatment, is prescribed in patients with traumatic [....] » Read More
The number of children diagnosed with Autism Spectrum Disorder (ASD) is increasing worldwide. While the challenges faced by English as a second language (ESL) learners are well-documented, little attention has been paid to those with ASD as they learn the language. This research [....] » Read More
Background and purpose: SWI can help in the diagnosis of thrombus within the vessel in acute ischemic stroke (AIS) known as susceptibility vessel sign (SVS) and detection of SVS within the vessel can predict treatment modality and outcome. In this study, the purpose is to correl [....] » Read More
In this oral presentation, I will explore the intriguing relationship between prolonged antibiotic use, the gut-brain axis, and cognitive function in healthy individuals. The gut-brain axis, a fascinating bidirectional communication system between the gut and the brain, has emerg [....] » Read More
Introduction: We present a case of pseudoaneurysm of the facial artery after tonsillectomy managed with successful endovascular coiling. Presentation of Case: 41-year-old lady presented with a history of throat pain and 3 episodes of hematemesis on the 3rd, 4th, and 7th post [....] » Read More
Introduction: Susac syndrome; It is a rare disease that is characterized by the triad of encephalopathy, sensorineural hearing loss and branch retinal artery occlusion, which is thought to develop due to immune-mediated microangiopathy. It is more common in patients aged 16-40 [....] » Read More
In this work, different points will be orderly discussed: Quantifications technics of heavy metals: Arsenic (As), Chromium (Cr), Iron (Fe), Mercury (Hg), Cadmium (Cd), Aluminum (Al), Zinc (Zn), Nickel (Ni), lead (Pb), and copper (Cu), via the X-ray fluorescence spectroscopy [....] » Read More
Motor Nerve conduction study is one of the electrophysiological tests performed to evaluate electrical conduction of motor nerves. Many studies involved nerve conduction velocity of peripheral nerves, but only few addressed this issue in relation to handedness with lots of contro [....] » Read More
SARSCoV2 the virus responsible for the COVID19 pandemic had not only respiratory symptoms,butalso neurological symptoms, and headache is a frequent complaint.Pathophysiologyof headache in the context of COVID 19 has some mechanisms that can be involved in persistence of headache [....] » Read More
Design to facilitate the recognition of congruent prosthetic movements, context-to-motion translations guided by image, verbal prompt, users nonverbal communication as facial expressions, gestures, paralinguistics, scene context and object recognition contributes to this process& [....] » Read More
Introduction: We present a case of chronic subdural hematoma refractory to burr hole surgery treated successfully with middle meningeal artery embolization. Presentation of Case: 61-year-old gentleman presented with a history of headaches and single episodes of vomiting. Ne [....] » Read More
Background: Intramedullary spinal cord ependymomas (IMSCE) are rare tumors that mostly occur in adult patients. Management strategies and related outcomes are heterogeneously reported across the literature, demanding a comprehensive analysis to standardize guidelines. We system [....] » Read More
Title : Introducing 4D printing for stem cell delivery to and function in the brain: Improving viability, differentiation, and brain function
Thomas J Webster, Interstellar Therapeutics, United States
Stem cells have not provided the universal, effective solution to neurological diseases that they were once thought to provide. In particular, maintaining stem cell viability during and after implantation into the brain has proved problematic. The use of enzymes (such as trypsin) [....] » Read More
Title : Use of MRI-navigated Transcranial Pulse Stimulation (TPS) as an alternative treatment for alzheimer’s disease and other psychiatric diseases
Ulrich Sprick, Alexius/Josef Clinic, Germany
Dementia is still one of the most common serious psychiatric disorders in old age. A dementia of the Alzheimer's type is still considered to be a progressive irreversible disease which cannot be treated causally. However, in the meantime it has been shown that novel non-invas [....] » Read More
Title : Calcium signaling in diabetic vascular dementia
Yong Xiao Wang, Albany Medical College, United States
Vascular dementia, also known as vascular contributions to cognitive impairment and dementia (VCID), is a neurodegenerative disease. VCID has high morbidity and mortality. Diabetes is a leading factor in the development of VCID. However, the cellular and molecular mechanisms unde [....] » Read More
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model to be set up to secure the human healthcare, wellness and biosafety through the view of public health
Sergey Suchkov, Moscow State University of Food Industry (MGUPP), Russian Federation
A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, personalized and precision medicine (PPM). To achieve the implementation of PPM concept, it is necessary to create a fundamentally new strategy based upon the r [....] » Read More
Title : Clinical evidence supporting cannabis/cannabinoids for treating neurological disorders
Jag H Khalsa, GWU School of Medicine and Health Sciences, United States
Cannabis continues to be the most abused illicit drug in the world with an estimated 2.5% of the world’s population (180 million) using it regularly (World Drug Report 2017)1. Medicinal and/or recreational cannabis use is associated with significant health consequences) (WH [....] » Read More
Title : Aging with disability: Early- onset acquired brain injury
Didem Inanoglu, Franciscan Childrens, United States
Children with special health-care needs (CSHN) have or are at increased risk for chronic physical, developmental, behavioral, or emotional conditions and also require health and related services of a type or amount beyond that required by their peers. Acquired brain injury (ABI) [....] » Read More
Title : Treatment with rhFGF18 appears cerebroprotective in model of ischemic stroke
Alex Goraltchouk, Remedium Bio, United States
Objective: In this study, we aimed to directly compare the safety and efficacy potential of two novel investigational treatment regimens for cerebral ischemia - rhFGF18 and rhGDF11, using a model of ischemic stroke. Background: Despite recent advances in prevention and treat [....] » Read More
Title : Combatting “Neurophobia”: A proposed educational model to promote “Neurophilia”
Richard I. Suarez, Florida International University, United States
When we reflect on medical education as a whole, novelty in structure and content promotes growth and enhances student outcomes. The teaching of neurology is no different and presents a more unique hurdle in its instruction considering the well-described phenomenon of “neur [....] » Read More
Title : The role of gut microbes in vascular dementia
Navdeep Kaur, Cleveland Clinic Foundation, United States
Stroke is the second most common cause of cognitive impairment and dementia. Vascular dementia (VaD), a cognitive impairment following a stroke is common and substantially affects the quality of life. We recently demonstrated via gut microbe transplant studies that the gut microb [....] » Read More
Title : Silent discos for dementia care: An accessible tool for music engagement
Anish Ganesh, The Dementia Project, United States
The symptoms of dementia often create a barrier between People Living with Dementia (PLWD) and their caregivers, which fuels a cycle of worsening outcomes for both parties. Care partners need a tool that alleviates this communication barrier to improve behavioral outcomes and qua [....] » Read More
Title : rsfMRI: Alternate to clinical task based fMRI
Mohit Saxena, Northwestern Medicine, United States
Introduction: Brain surgery may benefit from functional MRI (fMRI) that can detect changes in cerebral blood flow and oxygen utilization caused by tissue activation. Therefore, the patient needs to perform certain tasks in the scanner while fMRI is acquired. However, task-based [....] » Read More
Title : Investigating the molecular mechanisms involved in early events of cellular dysfunction in alzheimer's disease
Muhammad Yahya Saif, Aston University, United Kingdom
Alzheimer’s Disease (AD) is a progressive neurological disorder that gradually deteriorates cognitive abilities and leads to the inability to carry out simple tasks. However, the molecular mechanisms and causes of this disease are still unclear. This research aims to use th [....] » Read More
Title : Neuroimaging by evaluation nerverenovate and neuroplasticity of acupuncture in children with cerebral palsy
Zhenhuan Liu, Guangzhou University Chinese Medicine, China
Objective: To investigate the effect of and Acupuncture on brain plasticity and motor development in children with cerebral palsy. Investigate effect on mechanism of apoptosis of brain nerve cells, regulating the expression of neurotrophic factors, promoting the remodeling [....] » Read More
Title : Effects of transcranial pulse stimulation on autism spectrum disorder: a double-blind, randomized, sham-controlled trial
Teris Cheung, The Hong Kong Polytechnic University, Hong Kong
Transcranial pulse stimulation (TPS) has been proven effective to improve cognition, memory and depressive symptoms on Alzheimer’s disease, but supporting evidence on other neurological diseases or neuropsychiatric disorders remains limited. We aimed to investigate the effe [....] » Read More
Title : Evaluating the efficacy of Electrical Vestibular Stimulation (VeNS) on insomnia adults: A double-blind, randomized, sham-controlled trial
Teris Cheung, The Hong Kong Polytechnic University, Hong Kong
Insomnia is a common health problem in the general population. There are different ways to improve sleeping habits and quality of sleep, however; there is no clinical trial using transdermal neurostimulation to treat individuals with symptoms of insomnia in Asia. This gave us the [....] » Read More
Title : To evaluate the effect of endothelin receptor agonist IRL-1620 alone and in combination with donepezil in modulating neurodegeneration produced by amyloid-? in rats
Eshani Mahajan, Postgraduate Institute of Medical Education and Research-PIGMER, India
IRL-1620 is a chemical entity that have neuroprotective activity as it increases growth factors VEGF and NGF. The Present study hypothesis is to evaluate the effect of IRL-1620 on Aß induced memory loss in the rat model of Alzheimer’s disease. We have taken 58 males a [....] » Read More
Title : Oxygen extraction fraction: Review on different computational methods based on mGRE sequences and clinical manifestations
Farsana F J, Digital University Kerala, India
Oxygen extraction fraction (OEF) is a physiological biomarker reflecting the percentage of oxygen extracted from the blood supply, which is directly associated with cerebral oxygen metabolism. It can also provide information about the relative deficiencies in cerebral blood suppl [....] » Read More
Title : Prospective observational study on hyponatremia in Acute Encephalitis Syndrome (AES) in children: it's occurrence and effect on outcome
Nikita Diwan, King Georges's Medical University, India
Hyponatremia has been reported in various central nervous system infections like tuberculous meningitis and found to be associated with poor outcome. So far, no study has been conducted on hyponatremia in acute encephalitis syndrome (AES) in children. This study was planned to st [....] » Read More
Title : Use of NMDA antagonists for the treatment of TBI
Fernanda Cristina Poscai Ribeiro, Universidade do Oeste Paulista, Brazil
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity among individuals under 45 years of age worldwide. In the United States alone, approximately 1.7 million traumatic events occur annually, resulting in 50,000 deaths. This high prevalence of TBI poses a sig [....] » Read More
Title : The efficacy of botulinum toxin in treating trigeminal neuralgia: A comprehensive review
Camille Cipriano Vanini Tupinamba, Alfredo Nasser University, Brazil
Trigeminal neuralgia is a debilitating condition characterized by intense facial pain, primarily affecting the trigeminal nerve. It is one of the most excruciating chronic pain syndromes known to medicine. The conventional treatment options for trigeminal neuralgia often include [....] » Read More
Title : Design of a chip mimicking binocular rivalry-A perceptual cognitive function
Garima Kapur, Jaypee Institute of Information Technology, India
The human brain is able to adapt to new situations and learn new things. The purpose of the work is to investigate human brain adaptability and learning tendencies. The ability of the brain to learn, program, and adapt has been replicated using CMOS-based circuitry, Neuromorphic [....] » Read More
Title : Brain and neurological disorder, types, causes, effects and possible solutions
Christine Akumcha Tekum, Maarif International School of Equatorial Guinea, Equatorial Guinea
There are many types of brain diseases, from injuries and infections to brain tumors. They can impact your ability to function and carry out daily activities. Outcomes vary widely depending on the type of brain disease, location and severity of the condition. The brain is [....] » Read More
Title : Chrysin attenuates the oxidative stress and neuronal apoptosis related to the reductions of hippocampal neurogenesis in D-galactose-induced brain aging
Ram Prajit, Khon Kaen University, Thailand
Brain aging is related to oxidative stress that leads to neuronal apoptosis and cognitive dysfunction. Neurogenesis occurs throughout the lifespan in the subgranular zone of the hippocampal dentate gyrus and it is gradually reduced in brain aging. Long term administration of D-ga [....] » Read More
Title : Expressions of several sets of microRNAs get perturbed when differentiated astrocytoma are exposed to NMOSD patient sera with different seropositivity – A functional analysis
Pallavi Chatterjee, Saha Institute of Nuclear Physics, India
Neuromyelitis Optica Spectrum Disorder (NMOSD), is a rare auto-immune demyelinating disorder of the Central Nervous System. A circulating auto-antibody (AQP4-IgG) against aquaporin-4 (AQP4) is found in more than 80% patients. Other auto-antibodies like the one against Myelin ol [....] » Read More
Title : Identification of the potential drug against candidate protein in sporadic ALS: A neurodegenerative disease using Integrative bioinformatics approach
Shazia Haider, Jamia Millia Islamia, India
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease observed due to the loss of upper and lower motor neurons. ALS is a multigenic disorder and its complex mechanisms are still clearly unknown. Despite recent scientific advancements some aspects of ALS pathogenic t [....] » Read More
Title : Optimal duration for recording pediatric EEG: An observational study
Arvinder, AIIMS, New Delhi, India
Objective To evaluate optimal duration for recording pediatric EEG in outpatient settings for children and adolescents aged 1month-18years. Methods Setting: Outpatient EEG Laboratory at Department of Pediatrics at a tertiary care teaching centre in north India. Exclusion cr [....] » Read More
Title : Intracerebral hemorrhage and COVID-19 infection: clinical characteristics and mortality from intensive care patients: Retrospective cohort review
Mohamed Fathi Al Gharyani, Benghazi Medical Center, Libyan Arab Jamahiriya
Background: Since the COVID-19 pandemic, many studies have reported severe neurologic effects of the infection on the brain. Intracerebral haemorrhage (ICH) is a particular pathology that can result in these devastating neurologic effects and affected patients are more likely to [....] » Read More
Title : The effects of cognitive behavioral therapy with biofeedback therapy on the quality of life, anxiety, depression and somatic symptoms in patients with dyssynergic defecation: A randomized controlled trial
Afsaneh Nikjooy, Iran university of medical sciences, Iran (Islamic Republic of)
Background: Dyssynergic defecation (DD) is a major cause of chronic functional constipation. Patients with DD have greater psychological distress and impaired health-related quality of life compared with the general population. This study aimed to evaluate the effectivene [....] » Read More
Title : Effect of thymosin ?4 on lipopolysaccharide-stimulated brain microvascular endothelial cells remodeling: A possible role in blood-brain barrier injury
Sudhiranjan Gupta, Biomarkers & Genetics Core, United States
War Veterans are particularly more prone for mental illnesses due to their prior encounters with multiple traumatic brain injuries (TBI) while serving on active duty specifically in the war zone areas. TBI is known to cause mortality or serious neurological disabilities among sur [....] » Read More
Title : What will audience learn from your presentation? • This case report will also present a review of recent literature revolving around PBA which will help other physicians and professionals understand and further include PBA as a diagnosis when assessing a patient demonstrating involuntary episodes of laughing and crying status-post a traumatic brai
Shayanthan Sornalingam, Meditech International, Canada
Pseudobulbar affect (PBA), previously known as Pathologic Laughing and Crying (PLC) is a neurological disorder characterised by involuntary episodes of emotional expression, such as laughing or crying, that are disproportionate to the individual's current emotional state. Tho [....] » Read More
Title : Economic impact of the first pass effect in mechanical thrombectomy for acute ischaemic stroke treatment
Eva Maria Gonzalez Diaz, Cruces University Hospital, Spain
Objective: The clinical benefit of mechanical thrombectomy(MT) in acute ischemic stroke treatment, is correlated to the degree of reperfusion achieved. The First Pass Effect (FPE) is defined as complete/near revascularisation of the large-vessel occlusion [modified Thrombolysis [....] » Read More
Title : Neuroblasts migration under control of reactive astrocyte-derived BDNF: A promising therapy in late neurogenesis after traumatic brain injury
Chongjie, Chongqing Medical University, China
Background: Traumatic brain injury (TBI) is a disease with high mortality and morbidity, which leads to severe neurological dysfunction. Neurogenesis has provided therapeutic options for treating TBI. Brain derived neurotrophic factor (BDNF) plays a key role in neuroblasts migra [....] » Read More
Title : Finding anatomical relations between brain regions using AI/ML techniques and the ALLEN NLP API
Bharath Kumar Nagaraj, Revature LLC, United States
Introduction The brain is a complex organ with a vast network of interconnected neurons. These connections allow different brain regions to communicate with each other, which is essential for many cognitive functions. However, the anatomical relationships between brain regions [....] » Read More
Title : Antibody-Proteases as the upgraded translational tools of the next-step generation in personalized and precision practice to monitor multiple sclerosis at clinical and subclinical stages
Sergey Suchkov, Moscow State University of Food Industry (MGUPP), Russian Federation
Biomarkers enable pre-early diagnosis, guide targeted therapy and monitor the active ty and therapeutic responses across the diseases. Among the best-validated predictive biomarkers are autoimmunity-related ones to predict and prognosticate risks of the chronification, complicati [....] » Read More
Title : Finding anatomical relations between brain regions using AI/ML techniques and the ALLEN NLP API
Naveen Kunchakuri, EchoStar Corporation, United States
Introduction The brain is a complex organ with a vast network of interconnected neurons. These connections allow different brain regions to communicate with each other, which is essential for many cognitive functions. However, the anatomical relationships between brain regions [....] » Read More
Title : Astrocytes have neuroimmunological function in the stab wound mouse brain
Hiroko Ikeshima Kataoka, Kieo University, Japan
Background: Some glial cells such as astrocytes and microglial cells activated when the traumatic injury occurred to the brain. After the stab wound to the mouse brain, those glial cells proliferate and secrete some of the inflammatory cytokines, however the functional role of th [....] » Read More
Title : Systematic review on the role of the glymphatic system in sleep-related disorders
Sagarika Gopalkrishnan, Einstein Medical Centre, United States
Objective: The aim of the study is to assess the implication of dysfunction in the glymphatic system in patients suffering from sleep-related disorders. The secondary aim is to understand the association between the glymphatic system and cognitive decline in patients with sleep- [....] » Read More
Title : A case report of faciobrachial dystonic seizures in an elderly patient with autoimmune encephalitis
Nadeem Akhtar, NHS UK, United Kingdom
A 73-year-old woman with pernicious anaemia was admitted to the hospital with Involuntary twitching for the past four weeks. According to her husband, she had also been confused as she had trouble recognising family members. Additionally, she developed headaches as well as involu [....] » Read More
Title : Artificial intelligence / Machine Learning (AI/ML) has the potential to predict the risk for stroke, days before the symptoms appear
Raj Gopalan, BSRM Consulting, United States
Background There are 12 million new stroke occurrences every year. 100 million people are living with stroke aftermath worldwide. $900 million are spent on stroke every year. 85% of strokes have no warning signs. 2 million neurons are lost every minute after stroke. If the tre [....] » Read More
Title : Trend in stroke incidence and admission blood glucose in louisiana
Ifechukwude Biose, Louisiana State University Health Sciences Center, United States
Introduction: Stroke is still a major cause of debilitating disability despite advancements in available clinical therapies. Raised admission blood glucose concentration is associated with poor outcomes of stroke, even in non diabetics. Hence, reporting stroke burden and outcome [....] » Read More
Title : Neuro-exergaming for parkinson’s: Clinic-observed trend of cognitive improvement after pedal-n-play with the interactive Physical and Cognitive Exercise System (iPACES)
Cay Anderson-Hanley, Union College & iPACES, United States
Given that approximately 40% of Parkinson’s patients may meet criteria for mild cognitive impairment (MCI) and 80% may progress to dementia (Kenney et al., 2022), researchers have pursued interventions that might stave off or ameliorate neuropsychological decline. Numerous [....] » Read More
Title : Estrogen Receptor Alpha (ER?) signaling in dendritic cells modulates autoimmune encephalomyelitis disease phenotype in mice
Shehata Anwar, University of Illinois at Urbana Champaign, United States
Estrogen is a disease-modifying factor in multiple sclerosis (MS), and its animal model, the experimental autoimmune encephalomyelitis (EAE), via estrogen receptor alpha (ERα). However, the mechanisms by which ERα signaling contributes to changes in disease pathogenes [....] » Read More
Title : CCR5-mediated T Cell infiltration into the brain triggers pulmonary dysfunction in murine cryptococcus-associated IRIS
Makoto Inoue, University of Illinois at Urbana-Champaign, United States
Cryptococcus-associated immune reconstitution inflammatory syndrome (C-IRIS) is identified upon immune reconstitution in immunocompromised patients who have previously contracted an infection of Cryptococcus neoformans (Cn). C-IRIS can be lethal, but how the immune system t [....] » Read More
Title : Addressing education and medication adherence for stroke survivors
Mikaela Atkins, Arizona State University, United States
At one of the largest hospitals in Arizona, who care for individuals suffering from neurological diseases and houses a Joint Commission Comprehensive Stroke Center, the Comprehensive Stroke Program Quality Team has been working in conjunction with an Arizona State University Doct [....] » Read More
Title : Cryoneurolysis in restless legs syndrome: A case report of intermediate to long-term relief in 2 patients
Carmen Vogt, University of Nebraska Medical Center, United States
Restless Legs Syndrome (RLS) is associated with uncomfortable sensations in limbs that result in a sudden urge to move. The underlying etiology is unknown but is thought to be influenced by genetics, pregnancy, iron deficiency, and alterations in nerve hyperexcitability or inhibi [....] » Read More
Title : Prenatal nicotine exposure during pregnancy results in adverse neurodevelopmental alterations and neurobehavioral deficit
Alicia C Well, University of California, United States
Maternal tobacco use and nicotine exposure during pregnancy have been associated with adverse birth outcomes in infants and can lead to preventable pregnancy complications. Exposure to nicotine and other compounds in tobacco and electronic cigarettes (e-cigarettes) has been shown [....] » Read More
Title : Combination treatment with electroconvulsive therapy and novel neuroactive steroid ganaxolone for cryptogenic new-onset refractory status epilepticus
Ariyaneh Nikbin, Albert Einstein College of Medicine, United States
Rationale: New-onset refractory status epilepticus (NORSE) is a neurologic emergency and potentially life-threatening syndrome described as continuous seizures in a previously healthy patient. Despite extensive workup, no specific etiology is found in over half of cases of NORS [....] » Read More
Title : Effect of resistance training on parkinson’s disease motor symptoms
Noor Abdulhameed, The University of Toledo College of Medicine & Life Sciences, United States
Parkinson’s disease (PD) is a progressive neurological movement disorder, with idiopathic onset, that impairs activities of daily living with nearly 10 million individuals diagnosed worldwide according to the Parkinson’s Foundation. Underlying pathology manifests du [....] » Read More
Title : Moya moya and atherosclerosis
Aliaa Mousa, Capital Health, United States
Introduction In the literature, there are not so many cases that connected Atherosclerosis to MMDandit hasn’t been assured by pathological studies as well. Moya Moya disease is a uniquecerebrovascular disease characterized by progressive large intracranial artery narrowing [....] » Read More
Title : Chronic subdural hematoma drainage under local vs. General anesthesia: Systematic review and meta-analysis
Amy Zhou, University of Saskatchewan, Canada
Introduction Chronic subdural hematoma (cSDH) is one of the most encountered conditions seen in neurosurgery. Although mainstay treatment of cSDH has been burr hole drainage, no consensus yet exists on optimal anesthesia technique for surgical treatment. Currently, the decision t [....] » Read More
Title : Individualisation of antiepileptic drugs and the role of levetiracetam in women with epilepsy
Nadiah Ghazalli, GSK Pharmaceuticals Sdn Bhd, Malaysia
Active epilepsy among women of childbearing age is more prevalent compared to the general population worldwide. Women with epilepsy (WWE) face specific challenges related to hormonal function, and by extension, their sexual and reproductive health. The impact of epilepsy and anti [....] » Read More
Title : Mechanisms of T cell-mediated brain neuronal damage in murine cryptococcus-associated iris
Jinyan Zhou, University of Illinois at Urbana Champaign, United States
Cryptococcus-associated immune reconstitution inflammatory syndrome (C-IRIS) is a condition that frequently occurs in immunocompromised patients infected with Cryptococcus neoformans (Cn), whose immune systems become overreactive upon reconstitution. Patients contracted with C-IR [....] » Read More
Title : Human iPSC-derived microglia chimeric mouse as a translatable in vivo model
Nanxia Zhao, Biogen, United States
Microglia are resident macrophages of the brain parenchyma that is involved in many critical CNS functions, ranging from supporting neurogenesis and synapse remodeling to direct modulation of myelination and phagocytosis. Due to its reactive response to disease state and neuronal [....] » Read More
Title : A rare case of arnold-chiari malformation evident after a streptococcal throat infection in a young female: A case report
Maryam shahab, Central Park Physicians, United States
Arnold-Chiari malformation is a rare neurological developmental disorder that presents at birth. No such cases have been reported in support of microbial infections causing Chiari malformation; yet there is evidence how microorganisms can lead to brain abscess, brain empyema, and [....] » Read More
Title : Effect of add-on melatonin on seizure outcome, neuronal damage, oxidative stress and quality of life in generalized epilepsy with generalized onset motor seizures in adults: A randomized controlled trial
Rituparna Maiti, All India Institute of Medical Sciences, India
Background: Epilepsy treatment is challenging because of multiple impediments like lack of efficacy of monotherapy, adverse drug reactions, and different co-morbidities. Add-on therapy to first-line antiepileptics may be the option to overcome therapeutic hurdles. The present ra [....] » Read More
Title : Treatment challenges for EGFR-mutant NSLC and LMD: When adverse reactions prevent targeted therapy
Vatsala Kapoor, Medical College of Georgia, United States
Purpose: To review the optimal treatment of EGFR-mutant non-small cell lung cancer (NSCLC) that has progressed to leptomeningeal disease (LMD) through a rare case presentation and literature review. Background: LMD, the spread of cancer into the leptomeninges, is a rare compli [....] » Read More
Title : CRISPR desingning your Grna FOR CAS 9 genome editing using DNA sensors to detect cerebrospinal fluid morbiditidity invitro viral gene transmission
Nisha mithal, Stanford Medicine Neuroradiology, United States
CRISPR technology has made it easier than ever both to engineer specific DNA edits and to perform functional screens to identify genes involved in a phenotype interest. We will discuss differences between these approaches, and provide updates on how best todesign gRNAs. The hamme [....] » Read More
Title : Multisutural cranial reconstruction in a case of crouzon syndrome with complex craniosynostosis and no mutations: A case report
Hari Om Vaja, B.J. Medical College, India
The discussion during the presentation will be of a case of a 5-year-old male child diagnosed with Crouzon syndrome and complex craniosynostosis, which involved the fusion of multiple sutures, including metopic, bi-coronal, sagittal, and lambdoid. Karyotyping showed no mutations [....] » Read More
Title : The neuroprotective properties of rosmarinic acid against cognitive impairments and hippocampal neurogenesis caused by L-methionine in adult rats
Apiwat Sirichoat, Khon Kaen University, Thailand
L-methionine (L-met) is one of the nine essential amino acids. A high dose of supplementary methionine administration over a long period can promote oxidative stress due to increasing base levels of metabolites, such as homocysteine (Hcy). Homocysteine contributes to neuronal cel [....] » Read More
Title : New born infantile spasms: Aicardi syndrome | A case report
Keanne Paula H. Amamanglon, Makati Medical Center, Philippines
Aicardi syndrome (AS) is an exceedingly rare genetic disorder characterized by ocular fundus abnormalities, seizures, and corpus callosum agenesis. The condition is sporadic, and the precise gene mutation has not been identified; however, clinical findings provide a high index of [....] » Read More
Title : The role of Vasoactive Intestinal Peptide (VIP) and Pituitary Adenylate Cyclase-Activating Polypeptide (pacap) in chronic and episodic migraines: A meta-analysis
Sangharsha, Westchester Medical Center, United States
Background Migraine is a disabling neurological disorder without blood-based susceptibility markers. We aimed to evaluate the possible biomarker role of neuropeptides, vasoactive intestinal peptide (VIP), and pituitary adenylate cyclase-activating polypeptide (PACAP) in chronic [....] » Read More
Title : Safety and efficacy of tenecteplase versus alteplase for thrombolysis in acute ischemic stroke: Single center experience
Abigail C Hasan, Jamaica Hospital, United States
Background: Thrombolytic therapy has been the gold standard for treatment of ischemic stroke since 1996. While alteplase (tPA) remains the only FDA-approved thrombolytic for acute ischemic stroke, recent studies suggest that tenecteplase (TNK) may be a preferable alternative bec [....] » Read More
Title : Sleep quality in medical students: A comparison across the different semesters using the Pittsburgh Sleep Quality Institute (PSQI)
Miranda Montion, Ross University School of Medicine, United States
Background: Sleep quality as a lifestyle metric to predict severity of disease burden, development, and prevention has become a new focus in literature. Low sleep quality, total hours of sleep per night, and perceived stress have been implicated in disease progression and diagn [....] » Read More
Title : Cerebral vasculitis in the setting of recurrent hashimoto’s encephalopathy
Anna Siddiq, VCOM - Auburn, AL, United States
Introduction: Hashimoto encephalopathy is a rare autoimmune condition characterized by symptoms such as confusion, seizures, and headache. It can lead to cerebral vasculitis causing the blood vessels in the brain to become inflamed and lead to decreased blood flow with potential [....] » Read More
Title : Familial CJD in three generations.
Neetika Sharma, PGIMER, India
59 yrs old male presented with 11 months history of ataxia followed by 3 months history of bilateral hand action tremors. 9 month into illness he started to have cognitive decline followed by myoclonic jerks . He also had fragmented sleep with decreased total sleep duration. He h [....] » Read More
Title : Prunus domestica L. extract diminishes deteriorations of memory and hippocampal neurogenesis in D-gal-induced aging in a rat model
Jariya Umka Welbat, Khon Kaen University, Thailand
Memory loss is the most common symptom found in aging. Studies of brain aging have revealed upregulation of the reactive oxygen species levels, which induce oxidative stress, neuronal damage, and neuronal apoptosis linked to memory decline. In animal studies, Dgalactose (D-gal) c [....] » Read More
Title : Study of support for children with developmental dyslexia symptoms in Japanese and its effectiveness
Ayako Fukuda, Dokkyo University, Japan
There are three types of Japanese characters: hiragana, katakana and kanji. Of these, hiragana is said to be easier to be acquired because of its regularity and one-to-one correspondence between letters and sounds (Uno et al., 2009). Therefore, early identification and support of [....] » Read More
Title : Development and validation of an immunoassay for the selective quantification of tau aggregates in alzheimer’s disease
Md Tohidul Islam, University of Gothenburg, Sweden
Tau aggregation into neurofibrillary tangles (NFTs) and paired helical filaments (PHFs) is a defining feature of Alzheimer’s disease (AD). However, biochemical assays for the quantification of pre-NFT/PHF tau aggregates are lacking. We describe an immunoassay that is select [....] » Read More
Title : Center of pressure oscillations reveal the potential factors of loss of automaticity in older adults
Alexander Guo, Boise State University, United States
Falls are a significant global health issue for older adults. Most falls among older adults occur during dual-task activities. This could be attributed to the reduced automaticity in postural control among older adults. Identifying potential factors contributing to the loss of au [....] » Read More
Title : Exploring neurocognitive disruptions in Herpes Simplex Virus-Induced Encephalosynaptic Syndrome (HESINES)
Ryan Forster, Albert Einstein College of Medicine, United States
Our recent work has uncovered a novel aspect of Herpes Simplex Virus (HSV) pathology - the Herpes Simplex Virus-Induced Encephalosynaptic Syndrome (HESINES). This syndrome reveals a complex interplay between viral particles and neuronal circuitry, leading to a range of unique man [....] » Read More
Title : Synthetic GM1 treatment of mice deficient in GM3 synthase (GM3S)
Suman Chowdhury, The State University of New Jersey, United States
Glycosphingolipids containing sialic acids are called gangliosides. They are primarily found in neural tissues, especially brain tissues. GM1, GD1a, GD1b, & GT1b gangliosides are commonly found in brain tissues. In many nonneural tissues, GM3, which is the precursor for these [....] » Read More
Title : Study on the correlation between PM2.5 exposure and incidence of alzheimer’s disease among seniors
Li Yang, Zhejiang University School of Medicine, China
Studies have shown that PM2.5 may be associated with various neurogenic diseases represented by senile dementia. However, this topic has been little studied in Zhejiang and lacks scientific support. We established a cohort of Alzheimer’s Disease (AD) high-risk population in [....] » Read More
Title : Behind the symptoms: Decoding moyamoya disease in an adult female
Dominique Hayduk Montecino, Lakeland Regional Health, United States
Background: We report a case of a middle-aged woman admitted due to near syncope who presented with transient neurological symptoms for months, but had an unremarkable initial neurological examination in the emergency room. Subsequent advanced imaging unveiled a diagnosis of Mo [....] » Read More