David Joseph Sperbeck, Private practice, United States
Recovery from brain trauma is in part dependent upon the brain’s ability to adapt to new and challenging experiences. The brain’s capacity to structurally and functionally reorganize nerve cells and spontaneously develop new neuronal networks defines neuroplasti [....] » Read More
Title : The role beliefs, perception, biases, prejudices and patterns of behaviour play in the incubation of and the evolution of psychophysical diseases and disorders
Ken Ware, NeuroPhysics Therapy Institute and Research Centre, Australia
Did the patient genetically inherit their complex psychophysical pathological condition/s or are they simply adopting and/or mirroring other members of their family who have the complex psychophysical condition that the patient is exhibiting? Over several decades it has been f [....] » Read More
Title : Introducing 4D printing for stem cell delivery to and function in the brain: Improving viability, differentiation, and brain function
Thomas J Webster, Interstellar Therapeutics, United States
Stem cells have not provided the universal, effective solution to neurological diseases that they were once thought to provide. In particular, maintaining stem cell viability during and after implantation into the brain has proved problematic. The use of enzymes (such as trypsin) [....] » Read More
Title : Neural abnormalities, psychopathologies, and the unity of consciousness
Rocco Gennaro, University of Southern Indiana, United States
In this talk I first review several different notions of the “unity of consciousness” such as subject unity, object unity, spatial unity, and perhaps most common “phenomenal unity” which is the general notion that, from the first-person point of view, we e [....] » Read More
Title : Expanding the phenotypic spectrum of apmr4 syndrome caused by a novel variant in lss gene and review of literature
Engy Asem Ashaat, National Research Centre, Egypt
Alopecia intellectual disability syndromes 4 (APMR4) is a very rare autosomal recessive condition caused by a mutation in the LSS gene present on chromosome 21. This syndrome has a clinical heterogeneity mainly exhibited with variable degrees of intellectual disability (ID) [....] » Read More
Title : To evaluate the effect of endothelin receptor agonist IRL-1620 alone and in combination with donepezil in modulating neurodegeneration produced by amyloid-? in rats
Eshani Mahajan, Postgraduate Institute of Medical Education and Research-PIGMER, India
IRL-1620 is a chemical entity that have neuroprotective activity as it increases growth factors VEGF and NGF. The Present study hypothesis is to evaluate the effect of IRL-1620 on Aß induced memory loss in the rat model of Alzheimer’s disease. We have taken 58 males a [....] » Read More
Title : Management of adolescent idiopathic scoliosis in neurological disorder patient
Stephen Onyancha Kamanda, Kenyatta National Hospital, Kenya
Scoliosis is commonly described as a 3D spinal deformity resulting in a curvature of 10 degress or more with a rotational spin. All the bones in the body have three cells that work together for the proper growth of the bone: The osteocyte,cell that coordinates the osseous work [....] » Read More
Title : The effects of cognitive behavioral therapy with biofeedback therapy on the quality of life, anxiety, depression and somatic symptoms in patients with dyssynergic defecation: A randomized controlled trial
Afsaneh Nikjooy, Iran university of medical sciences, Iran (Islamic Republic of)
Background: Dyssynergic defecation (DD) is a major cause of chronic functional constipation. Patients with DD have greater psychological distress and impaired health-related quality of life compared with the general population. This study aimed to evaluate the effectiveness [....] » Read More
Title : Oxygen extraction fraction: Review on different computational methods based on mGRE sequences and clinical manifestations
Farsana F J, Digital University Kerala, India
Oxygen extraction fraction (OEF) is a physiological biomarker reflecting the percentage of oxygen extracted from the blood supply, which is directly associated with cerebral oxygen metabolism. It can also provide information about the relative deficiencies in cerebral blood suppl [....] » Read More
Title : Studies on traumatic brain injury: Fragments of VWF regulate the expression of adhesion molecules and modulate vascular permeability in stimulated endothelial cells
Marina Martinez Vargas, Baylor College of Medicine, United States
Von Willebrand factor (VWF) is a multimeric protein that mediates thromboinflammation and has been linked to traumatic brain injury (TBI), specifically in the pathogenesis of early brain injury. Activated endothelium secretes VWF multimers as long hyperadhesive strings. During TB [....] » Read More
Title : Arteriovenous malformations: An update on models and therapeutic targets
Brandon Lucke Wold, University of Florida, United States
Subarachnoid hemorrhage (SAH) continues to be a leading cause of morbidity and mortality, with cerebral vasospasm as a common etiology of worse clinical progression. The purpose of this study was to evaluate and review the current literature concerning the effective treatment of [....] » Read More
Title : Racial/Ethnic disparities in the alzheimer's disease link with heart disease and stroke, based on hawaii medicare population
Chathura Siriwardhana, University of Hawaii, United States
Background: There is an expanding body of literature implicating heart disease and stroke as a risk factor for Alzheimer disease (AD), highlighting significant pathways. Hawaii state has the most diverse ethnic population in the US and there exists significant racial health dispa [....] » Read More
Title : Intrathecal pain treatment & ziconotide
Georgios Matis, University Cologne Hospital, Germany
Ziconotide is a synthetic, water-soluble cone snail venom-derived peptide with a molecular weight of 2,639 Daltons. It is a nonopioid analgesic that selectively binds to N-type voltage-sensitive calcium channels on primary nociceptive afferent nerves in the dorsal horn of the spi [....] » Read More
Title : The efficacy of vestibular rehabilitation therapy for mild traumatic brain injury: A systematic review and meta-analysis
Ammar Aljabri, King Saud Bin Abdulaziz University for Health and Sciences, Saudi Arabia
Introduction: Mild Traumatic Brain Injury (mTBI) or concussion is a common yet undermanaged and underreported condition. This systematic review and meta-analysis aim to determine the efficacy of Vestibular Rehabilitation Therapy (VRT) as a treatment option for mTBI. Methods: T [....] » Read More
Title : Artificial intelligence and virtual reality Kinect rehabilitation in stroke patients with unilateral spatial neglect
Lama Saad El Din Mahmoud, October 6 University, Egypt
Background: People with neglect suffer from various spatial deficits in several modalities, which in many cases impair everyday functioning. Virtual reality (VR) is a form of interaction between humans and computers in which a real or imaginary environment is simulated. Users int [....] » Read More
Title : Deficits in behavioral and neuronal pattern separation in temporal lobe epilepsy
Swetha Ravi, Michigan State University, United States
In temporal lobe epilepsy, the ability of the dentate gyrus to limit excitatory cortical input to the hippocampus breaks down, leading to seizures. The dentate gyrus is also thought to help discriminate between similar memories by performing pattern separation, but whether epilep [....] » Read More
Title : Addressing education and medication adherence for stroke survivors
Mikaela Atkins, Arizona State University, United States
At one of the largest hospitals in Arizona, who care for individuals suffering from neurological diseases and houses a Joint Commission Comprehensive Stroke Center, the Comprehensive Stroke Program Quality Team has been working in conjunction with an Arizona State University Doct [....] » Read More
Title : Assessing the role of osteopontin in regulating cytokine expression among macrophages and neuroinflammatory pathways in HIV-Associated Neurocognitive Disorder (HAND)
David Zeng, Johns Hopkins University, United States
Previous work in humanized mouse models of human immunodeficiency virus type-1 (HIV-1) has demonstrated that knocking down the matricellular protein Osteopontin (OPN) in vivo leads to a robust increase in the expression of proinflammatory markers TSPO and AIF-1, suggesting that O [....] » Read More
Title : Clinical characteristics, management, and outcomes of intramedullary spinal cord ependymomas in adults: A systematic review
Mohammad Aadil Qamar, Ziauddin University, United States
Background: Intramedullary spinal cord ependymomas (IMSCE) are rare tumors that mostly occur in adult patients. Management strategies and related outcomes are heterogeneously reported across the literature, demanding a comprehensive analysis to standardize guidelines. We systemat [....] » Read More