Title : Posterior reversible encephalopathy syndrome or disseminated endotheliopathy perfusion syndrome: Time for a new name
Abstract:
In 1996, in this same city, Posterior Reversible Encephalopathy Syndrome (PRES) was presented as a new neurological condition. PRES has long been described as a benign clinico-radiological syndrome. However, in recent years, it has had an associated global mortality rate up to 19% of patients and a specific mortality rate of 5.7% directly correlated to the neurological condition.
Here, the authors suggest a name change from Posterior Reversible Encephalopathy Syndrome to Disseminated Endoteliopathy Perfusion Syndrome (DEPS) based on the radiological and neuropathophysiological findings. The name change presents a more accurate representation of what occurs and can help in explaining prognosis to other physicians and family members of the patient. Furthermore, the name change could contribute to the development of possible treatments to improve cerebral artery endothelium dysfunction observed on DEPS (PRES) patients, as physicians no longer expect the patient to recover to a complete neurological state.
