Normal brain development refers to the expected neurologic and cognitive maturation of the brain from birth to adulthood. It is the result of a complex interplay between genetic and environmental influences that direct cells to develop into structurally and functionally specialized regions of the brain. Neurodevelopment is a lengthy process that begins with cell proliferation and continues through the formation of synapses, neuronal networks, and neural pathways which mediate communication across different brain regions. During this time, the brain’s ability to adjust to changes in the surrounding environment by activating integrated behavioral and cognitive responses improves. Consequently, the normal brain’s capacity to form strong relationships with the people and environment comprising its life context is enhanced. In contrast to normal brain development, pathological brain development results from the acquisition of abnormalities or diseases that deface the brain’s structure and/or affects its cognitive, emotion, and/or social functioning. Common causes of pathological brain development include genetic disorders, neurodegenerative diseases, prenatal insult, traumatic brain injury, and exposure to environmental toxins. Such insults may lead to a range of disorders among which autism, epilepsy, and cerebral palsy are the most common. While the cognitive, emotional, and/or behavioral outcomes of abnormal brain development may not be immediately visible, these conditions often manifest as an individual grows leading, to a severe impairment of functioning. It is essential for neurological health practitioners to identify developmental deficits associated with neurological pathologies as early as possible as there are numerous treatment strategies that can be used to alleviate their severity. Thus, detailed comprehension of the course of normal brain development is necessary for the detection and management of neurological disease. Moreover, research into the interplay between genetic and environmental influences in neurodevelopmental disorders has yielded some promising results. For instance, a lot of research indicates that environmental enrichment and other lifestyle interventions may improve the cognitive development of those with neurodevelopmental conditions.
Title : Triple-network dysfunction, ME/CFS, and the NeuroPhysics Treatment Process “A dynamical systems perspective on psychophysical organization and environmental interaction”
Ken Ware, NeuroPhysics Therapy Institute and Research Centre, Australia
Title : ADNP regulates cortical development: Mechanism of ADNP syndrome/autism
Kazuhito Toyooka, Drexel University College of Medicine, United States
Title : Mild cognitive impairment (MCI) in Parkinson’s disease: Prevalence given MDS criteria
Cay Anderson Hanley, iPACES, United States
Title : Modeling early neurologic trajectories after elevated leg positioning (ELP): A secondary analysis of the LEG-UP randomized feasibility study
Kayode Ahmed, The University of Texas MD Anderson Cancer Center, United States
Title : Neuro-exergaming for non-verbal autism spectrum: A case study of neuropsychological function after 15 sessions of pedal-n-play iPACES
Cay Anderson Hanley, iPACES, United States
Title : Prescribing joy: The importance of integrating memory cafes into dementia care
Saul Beaumont, Massachusetts Advisory Council on Alzheimer's Disease and All Other Dementias, United States