The study of neurodegenerative diseases delves into the intricate processes of neuronal decline and dysfunction, exploring the mechanisms behind disorders like amyotrophic lateral sclerosis, multiple sclerosis, and frontotemporal dementia. Cutting-edge research highlights the role of protein misfolding, mitochondrial dysfunction, and neuroinflammation in disease pathology. Therapies targeting these pathways, including small molecules, gene therapies, and stem cell-based treatments, are at the forefront of clinical trials. Efforts to integrate neuroimaging and computational models enhance the understanding of disease progression, enabling the design of precise therapeutic interventions. Collaborative advancements are reshaping the future of managing and potentially reversing the effects of these complex disorders.
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany