Neuroinflammation, on the other hand, pertains to inflammation within the central nervous system (CNS), involving immune system cells and molecules. While inflammation is a natural response to injury or infection, chronic neuroinflammation can adversely affect brain function and contribute to various neurological disorders. Microglia, the CNS's resident immune cells, are pivotal in neuroinflammation. Upon activation, microglia release pro-inflammatory molecules like cytokines, chemokines, and reactive oxygen species, potentially harming neurons and other brain cells. Astrocytes, another glial cell type, can also contribute to neuroinflammation when activated. Neuroinflammation is implicated in numerous neurological disorders such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, and traumatic brain injury, where chronic inflammation exacerbates neuronal damage and disease progression. Understanding the mechanisms underlying neuroinflammation is crucial for developing novel therapeutic strategies. Researchers explore various approaches to modulate neuroinflammation, including targeting specific inflammatory molecules, regulating immune cell activation, and promoting neuroprotective pathways. These efforts hold promise for developing treatments to slow or halt the progression of neuroinflammatory disorders and foster brain health.
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Narrative medicine: A communication therapy for the communication disorder of Functional Seizures (FS) [also known as Psychogenic Non-Epileptic Seizures (PNES)]
Robert B Slocum, University of Kentucky HealthCare, United States
Title : Atypical presentation of Juvenile myoclonic epilepsy in a 16-year-old female: A Case Report
George Diaz, Memorial Healthcare Systems, United States
Title : Nanoparticles passing the blood brain barrier to treat cancer, infection, and more
Thomas J Webster, Brown University, United States
Title : Transcranial painless neurorehabilitation scalp acupuncture electrical stimulation for neuroregulation of autism spectrum disorder
Zhenhuan Liu, Guangzhou University Chinese Medicine, China
Title : Effects of prenatal androgen exposure on Purkinje cell morphology in the cerebellum of female rats
Kiran Ghotra, Lake Erie College of Osteopathic Medicine, United States