Inflammatory brain disorders encompass a broad spectrum of conditions characterized by inflammation within the brain tissue. This umbrella term includes ailments such as encephalitis, meningitis, and autoimmune disorders affecting the central nervous system (CNS). Encephalitis, for instance, involves inflammation of the brain parenchyma, often instigated by viral infections like the herpes simplex virus or autoimmune reactions where the body's immune system erroneously targets its own brain tissue. Meningitis, on the other hand, refers to inflammation of the protective membranes enveloping the brain and spinal cord, typically triggered by bacterial or viral infections. Autoimmune inflammatory disorders of the CNS, such as multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD), result from the immune system mistakenly attacking the myelin sheath, disrupting nerve signals and leading to various neurological symptoms like cognitive impairment, motor dysfunction, and sensory disturbances. Diagnosis of these disorders typically involves a thorough neurological examination, imaging studies such as MRI scans, and analysis of cerebrospinal fluid obtained via lumbar puncture. Treatment approaches vary depending on the underlying cause and may include antiviral or antibiotic medications, immunosuppressive therapy, and supportive care to manage symptoms and prevent complications. Early detection and intervention are paramount in minimizing brain damage and improving outcomes for patients with inflammatory brain disorders.
Title : A case of vile vindictive primary CNS vasculitis
George Diaz, Memorial Healthcare Systems, United States
Title : Novel important cellular responses, signaling mechanisms and therapeutic options in vascular dementia
Yong Xiao Wang, Albany Medical College, United States
Title : The role of beliefs, perception, and behavioural patterns in the evolution of psychophysical disorders
Ken Ware, NeuroPhysics Therapy Institute and Research Centre, Australia
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Krishna Moorjani, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Abhay Murthy, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signalling
Ethan Liu, Boston University, United States