12th Edition of International Conference on Neurology and Brain Disorders
October 20-22, 2025
Cerebral Blood Flow and Metabolism
Cerebral blood flow (CBF) is the blood transfusion to the brain in a given period of time. In an adult, CBF is typically 750 millilitres per minute or 15% of the cardiac output. This compare to an average perfusion of 50 to 54 millilitres of blood per 100 grams of brain tissue per minute.An increase in hydrogen ion concentration lead to increased cerebral blood flow. A decrease in blood viscosity will increase cerebral blood flow. An increase in carbon dioxide levels results in increased cerebral blood flow.
Metabolism depends on a continuous circulatory supply of glucose and oxygen to neurons and astrocytes. In astrocytes, glucose is partly converted to lactate, which is then released in the extracellular space and taken up by neurons.With neuronal activity, lactate oxidation increases.
Ken Ware
NeuroPhysics Therapy Institute and Research Centre, Australia
Joe Sam Robinson
Mercer University, United States
Robert B Slocum
University of Kentucky HealthCare, United States
Thomas J Webster
Interstellar Therapeutics, United States
Roger H Coletti
Interventional Health, PA, United States
Stephen Grossberg
Boston University, United States
George Diaz
Memorial Healthcare Systems, United StatesSubmit your abstract Today
Title : A case of vile vindictive primary CNS vasculitis
George Diaz, Memorial Healthcare Systems, United States
Title : Novel important cellular responses, signaling mechanisms and therapeutic options in vascular dementia
Yong Xiao Wang, Albany Medical College, United States
Title : The role of beliefs, perception, and behavioural patterns in the evolution of psychophysical disorders
Ken Ware, NeuroPhysics Therapy Institute and Research Centre, Australia
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Krishna Moorjani, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Abhay Murthy, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signalling
Ethan Liu, Boston University, United States