The process of brain development encompasses the intricate journey from conception to adulthood, characterized by the growth, connectivity, and maturation of the brain. It involves a sophisticated interplay of genetic, environmental, and experiential factors. During prenatal development, the brain initiates as a rudimentary structure, rapidly expanding and diversifying as neurons proliferate and migrate to their designated regions, establishing the foundational structure of the brain. Postnatally, the brain continues to evolve through various stages. Early childhood is distinguished by substantial synaptic pruning, wherein redundant connections are pruned while crucial ones are reinforced through experience-dependent plasticity, pivotal for acquiring fundamental skills and abilities. Throughout childhood and adolescence, the brain undergoes continual refinement and specialization, particularly in regions governing higher-order cognitive functions like the prefrontal cortex, which continues to develop into early adulthood, influencing decision-making, impulse control, and social behavior. Environmental influences, such as nutrition, stress, and sensory stimulation, profoundly shape brain development. Positive experiences, enriched environments, and nurturing relationships play a crucial role in fostering healthy brain development, whereas adverse experiences or neglect can impede progress and lead to developmental disruptions. Grasping the complexities of brain development is paramount for optimizing early childhood interventions, educational frameworks, and support systems to ensure individuals realize their full cognitive, emotional, and social potential.
Title : A case of vile vindictive primary CNS vasculitis
George Diaz, Memorial Healthcare Systems, United States
Title : Novel important cellular responses, signaling mechanisms and therapeutic options in vascular dementia
Yong Xiao Wang, Albany Medical College, United States
Title : The role of beliefs, perception, and behavioural patterns in the evolution of psychophysical disorders
Ken Ware, NeuroPhysics Therapy Institute and Research Centre, Australia
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Krishna Moorjani, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Abhay Murthy, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signalling
Ethan Liu, Boston University, United States