The Basal Ganglia System is an intricate and interconnected loop of specialized neurons and brain regions. It is located deep below the cortex, receives input from most parts of the brain and produces output to almost every area. One of the most important functions of the Basal Ganglia System is motor control. It plays a role in regulating movement by sending signals to the other motor control structures of the brain, such as the cerebellum and the thalamus. While scientists are uncertain of the exact mechanism, the Basal Ganglia System produces specific signals that are thought to be essential to the process and coordination of movement. The Basal Ganglia System is also involved in many other complex cognitive functions. It helps to shape our behaviors by sending signals to other areas of the brain which shape the way we feel and act. It is also involved in how we learn and the formation of memories. Additionally, the Basal Ganglia System is being studied for its involvement in some neurological disorders such as Parkinson’s disease. It is believed that the impaired functioning of the neurons within the Basal Ganglia System produces the characteristic symptoms of Parkinson’s, such as tremors and loss of motor control. Thanks to advances in technology and neuroscience, we now have a much better understanding of the intricate workings of the Basal Ganglia System. Continued research in this area is crucial to further our understanding of how the Basal Ganglia System is involved in controlling movement, shaping behavior, and forming memories and how it is disturbed in neural diseases.
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Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Krishna Moorjani, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Abhay Murthy, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signalling
Ethan Liu, Boston University, United States