Systems neuroscience incorporates different methods and different types of neurons, from receptors to cortical neurons, to investigate the functioning and organization of neurons of the nervous system. It is the study of neurons, their components, their organization, and the way in which they interact to produce behavior, cognition, and emotion. The main goal of systems neuroscience is to uncover the principle functional elements in the nervous system and better understand how neurons interact to create complex functions. This includes identifying the different structures of neurons that make up the nervous network and analyzing the flow of information within existing connections between neurons. Neuroscientists use a variety of techniques, including electrophysiology, modern imaging techniques, molecular approaches, pharmacological methods, psychophysics, and computer modeling. Systems neuroscience focuses on understanding the communication between the central nervous system and the peripheral nervous system, meaning neurons within the brain and spinal cord, those within muscles, and even those in the skin, eyes, ears, etc. It can also include the study of neuronal development, excitability, plasticity, and the neuropsychiatric aspects of mental and physical illnesses associated with different imbalances in neuronal networks. By combining these different elements from various fields, systems neuroscience can better understand how these might lead to a better understanding of sensory-motor function, memory, decision-making, emotion, and behavior. Understanding the network of the nervous system and the way it communicates together is the key to unlocking many of the mysteries of the brain and our ambition to improve our overall health.