Synaptic plasticity, the cornerstone of the brain's adaptability and learning prowess, refers to the dynamic changes occurring at neuronal junctions in response to activity. Long-term potentiation (LTP) and long-term depression (LTD) represent pivotal facets of synaptic plasticity, orchestrating the strengthening and weakening of synaptic connections, respectively. These mechanisms are fundamental to encoding and retaining information, forming the bedrock of memory and learning. However, dysregulation of synaptic plasticity is implicated in various neurological and psychiatric disorders, including Alzheimer's disease, schizophrenia, depression, and addiction, underscoring its significance in understanding disease pathogenesis and treatment development. Researchers are fervently exploring innovative strategies to modulate synaptic plasticity, aiming to rectify aberrant synaptic function in diseased states. By elucidating these mechanisms, targeted interventions could emerge, offering hope for ameliorating neural deficits associated with such disorders and enhancing patient outcomes.
Title : Managing healthcare transformation towards personalized, preventive, predictive, participative precision medicine ecosystems
Bernd Blobel, University of Regensburg, Germany
Title : Narrative medicine: A communication therapy for the communication disorder of Functional Seizures (FS) [also known as Psychogenic Non-Epileptic Seizures (PNES)]
Robert B Slocum, University of Kentucky HealthCare, United States
Title : Atypical presentation of Juvenile myoclonic epilepsy in a 16-year-old female: A Case Report
George Diaz, Memorial Healthcare Systems, United States
Title : Nanoparticles passing the blood brain barrier to treat cancer, infection, and more
Thomas J Webster, Brown University, United States
Title : Transcranial painless neurorehabilitation scalp acupuncture electrical stimulation for neuroregulation of autism spectrum disorder
Zhenhuan Liu, Guangzhou University Chinese Medicine, China
Title : Effects of prenatal androgen exposure on Purkinje cell morphology in the cerebellum of female rats
Kiran Ghotra, Lake Erie College of Osteopathic Medicine, United States