Synaptic plasticity, the cornerstone of the brain's adaptability and learning prowess, refers to the dynamic changes occurring at neuronal junctions in response to activity. Long-term potentiation (LTP) and long-term depression (LTD) represent pivotal facets of synaptic plasticity, orchestrating the strengthening and weakening of synaptic connections, respectively. These mechanisms are fundamental to encoding and retaining information, forming the bedrock of memory and learning. However, dysregulation of synaptic plasticity is implicated in various neurological and psychiatric disorders, including Alzheimer's disease, schizophrenia, depression, and addiction, underscoring its significance in understanding disease pathogenesis and treatment development. Researchers are fervently exploring innovative strategies to modulate synaptic plasticity, aiming to rectify aberrant synaptic function in diseased states. By elucidating these mechanisms, targeted interventions could emerge, offering hope for ameliorating neural deficits associated with such disorders and enhancing patient outcomes.
Title : Triple-network dysfunction, ME/CFS, and the NeuroPhysics Treatment Process “A dynamical systems perspective on psychophysical organization and environmental interaction”
Ken Ware, NeuroPhysics Therapy Institute and Research Centre, Australia
Title : ADNP regulates cortical development: Mechanism of ADNP syndrome/autism
Kazuhito Toyooka, Drexel University College of Medicine, United States
Title : Mild cognitive impairment (MCI) in Parkinson’s disease: Prevalence given MDS criteria
Cay Anderson Hanley, iPACES, United States
Title : Modeling early neurologic trajectories after elevated leg positioning (ELP): A secondary analysis of the LEG-UP randomized feasibility study
Kayode Ahmed, The University of Texas MD Anderson Cancer Center, United States
Title : Neuro-exergaming for non-verbal autism spectrum: A case study of neuropsychological function after 15 sessions of pedal-n-play iPACES
Cay Anderson Hanley, iPACES, United States
Title : Prescribing joy: The importance of integrating memory cafes into dementia care
Saul Beaumont, Massachusetts Advisory Council on Alzheimer's Disease and All Other Dementias, United States