Stroke and cerebrovascular diseases pose significant public health challenges, affecting millions worldwide and placing substantial burdens on healthcare systems. Stemming from disruptions in blood flow to the brain, these conditions lead to cascading events that can result in devastating neurological deficits and, in severe cases, death. Stroke, the most common cerebrovascular event, occurs when blood flow to a part of the brain is obstructed, either by a blood clot (ischemic stroke) or a ruptured blood vessel (hemorrhagic stroke). The consequences of stroke can be profound, ranging from paralysis and speech impairment to cognitive dysfunction and emotional disturbances. Beyond stroke, cerebrovascular diseases encompass conditions like transient ischemic attacks (TIAs), cerebral aneurysms, arteriovenous malformations (AVMs), and carotid artery stenosis. These conditions often share common risk factors such as hypertension, diabetes, smoking, obesity, and sedentary lifestyles. Early diagnosis and intervention are crucial in managing stroke and cerebrovascular diseases to mitigate brain damage and prevent long-term disability. Treatment strategies may include thrombolytic therapy, mechanical thrombectomy, and surgical interventions like carotid endarterectomy or stenting to restore blood flow in narrowed or blocked arteries.
Title : A case of vile vindictive primary CNS vasculitis
George Diaz, Memorial Healthcare Systems, United States
Title : Novel important cellular responses, signaling mechanisms and therapeutic options in vascular dementia
Yong Xiao Wang, Albany Medical College, United States
Title : The role of beliefs, perception, and behavioural patterns in the evolution of psychophysical disorders
Ken Ware, NeuroPhysics Therapy Institute and Research Centre, Australia
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Krishna Moorjani, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Abhay Murthy, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signalling
Ethan Liu, Boston University, United States