Neurocognitive Disorders, previously referred to as dementia, constitute a spectrum of conditions marked by cognitive deterioration significant enough to impede daily functioning. Alzheimer's disease, vascular dementia, Lewy body dementia, and frontotemporal dementia are prevalent forms of NCDs, each characterized by distinct pathological traits and clinical manifestations. These disorders stem primarily from neurodegenerative processes, cerebrovascular complications, or other cerebral pathologies. Symptoms encompass memory loss, executive dysfunction, language impairments, visuospatial challenges, and alterations in mood or behavior. The neurobiological underpinnings involve progressive neuronal loss, synaptic dysfunction, aberrant protein aggregation like amyloid-beta plaques and tau tangles, and neuroinflammation. Genetic predispositions, environmental factors, and lifestyle choices also contribute to NCD onset and progression. Timely diagnosis and intervention are pivotal for NCD management, though treatment options remain somewhat limited. Therapeutic strategies focus on symptom alleviation, cognitive stimulation, pharmacotherapy targeting neurotransmitter systems, and addressing modifiable risk factors such as hypertension, diabetes, and sedentary lifestyle. Moreover, providing supportive care and educating caregivers constitute vital aspects of NCD management to enhance patients' quality of life.
Title : Narrative medicine: A communication therapy for the communication disorder of Functional Seizures (FS) [also known as Psychogenic Non-Epileptic Seizures (PNES)]
Robert B Slocum, University of Kentucky HealthCare, United States
Title : Atypical presentation of Juvenile myoclonic epilepsy in a 16-year-old female: A case report
George Diaz, Memorial Healthcare Systems, United States
Title : Triple-network dysfunction, ME/CFS, and the NeuroPhysics Treatment Process “A dynamical systems perspective on psychophysical organization and environmental interaction”
Ken Ware, NeuroPhysics Therapy Institute and Research Centre, Australia
Title : In silico in vitro and in vivo study of geraniol role in Alzheimer's disease
Bhuvanesh Baniya, Mohanlal Sukhadia University, India
Title : Prince transform: a wave-mechanical framework for real-time EEG analysis and early seizure prediction using chirp and drift detection
Mustafa A Khan, Sevaro Health Inc., United States
Title : Gut-brain axis in autism spectrum disorder: MicroRNAs as a critical mediator of pathogenesis
Rahem Rahmati, Shahrekord University of Medical Sciences, Iran (Islamic Republic of)