Congenital neural diseases refer to illnesses that occur due to the development of abnormal neural structures or connections that occur during the embryonic period, in infants and children. These diseases can affect the cranial nerves, spinal cord, or brain and can be inherited or caused by external agents such as infections or toxins. Common examples include spina bifida, hydrocephalus, Cerebral palsy, Intellectual disability, Microcephaly and Neural Tube defects (NTDs). Spina bifida is a condition in which the neural tube does not completely close during development in utero, resulting in an open spine. This can lead to a variety of medical complications, particularly in the lower parts of the body that rely on nerve impulses. Hydrocephalus is a condition in which fluid builds up in the cavities within the skull, resulting in increased pressure and swelling of the brain tissue. This can cause impaired growth and intellectual disability. Cerebral palsy, a group of disorders affecting movement, posture, and muscle control, can also be a result of congenital neural diseases. It can be caused by a variety of genetic and environmental factors, including infection or damage to the brain in utero. Intellectual disability can be caused by both genetic and environmental factors. It can be caused by abnormalities in brain development, genetic and chromosomal abnormalities, environmental exposure to toxins, alcohol and drugs, or by complications during pregnancy or birth. Microcephaly is a condition in which the head circumference is smaller than the norm. It can be caused by genetic or environmental factors, such as infection or exposure to toxins. Neural tube defects are a group of birth defects caused by the incomplete development of the neural tube in the womb. NTDs can cause malformations of the spine, head, brain, and other parts of the nervous system. Treatment for these diseases may include medications, surgery, physical therapy, and genetic counseling.
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