The human brain is an incredibly complex and fascinating organ. A recent area of focus is its structural connectivity, or the way in which different parts of the brain are wired together. Structural connectivity can be studied using a variety of methods, including diffusion tensor imaging (DTI), magnetic resonance imaging (MRI), and positron emission tomography (PET). Structural connectivity is thought to play a role in various functions including memory, language, emotion, and decision-making. By examining the ways in which different brain regions are connected, researchers can better understand how these areas interact to produce complex behaviors. Additionally, understanding structural connectivity may provide insight into how the brain is wired and how it functions in certain disorders, such as autism spectrum disorders. DTI is the most widely used tool for mapping brain structural connectivity. It measures water diffusion as it moves in directions parallel to fibrous neural pathways. This data is used to compute an anisotropic diffusion tensor that helps to measure the overall connectivity of the pathways in a particular region of the brain. MRI and PET are also used to measure structural connectivity in the brain. MRI is used to generate detailed images of tissue and structures in the brain.
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Saul Beaumont, Massachusetts Advisory Council on Alzheimer's Disease and All Other Dementias, United States