The anterior cerebral artery(ACA) is a major blood vessel that supplies blood to the medial surface of the cerebral hemisphere, including the medulla, cortex, and frontal and temporal lobes. The blood is oxygenated through the coronary sinus and passes through the internal carotid artery before entering the ACA. The ACA originates from the internal carotid artery and branches into the anterior communicating artery, the anterior cerebral artery directly, and the callosomarginal artery. The anterior communicating artery connects the left and right ACA to allow for increased blood flow between the two hemispheres. The anterior cerebral artery is further subdivided into a superior division and an inferior division which separate into two lateral branches. The superior division of the anterior cerebral artery supplies blood to the medial surface of the frontal lobe while the inferior division supplies blood to the medial surface of the temporal and parietal lobes. The lateral branches of the anterior cerebral artery supply the anterior part of the corpus callosum and the anterior perforated substance. The anterior perforated substance is a region of gray matter which contains perforations through which arteries penetrate to directly supply blood to the thalamus and hypothalamus. The anterior cerebral artery is a significant source of blood to the brain as it plays a role in the perfusion of the frontal, temporal, and parietal lobes, as well as the corpus callosum and anterior perforated substance. It provides a critical connection between the left and right cerebral hemispheres, maintaining blood supply balance.
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