In the realm of neurovascular interventions, a gamut of procedures and techniques converge with the aim of diagnosing and addressing disorders afflicting the cerebral and spinal cord vasculature. Expertly executed by specialized healthcare practitioners, typically neurosurgeons or interventional neuroradiologists, these interventions stand as bulwarks against conditions such as strokes, aneurysms, and arteriovenous malformations (AVMs). Endovascular therapy emerges as a cornerstone, leveraging minimally invasive methodologies like catheterization to navigate the intricate labyrinth of cerebral vasculature, administering targeted treatments to the site of vascular aberrations. This encompasses an array of techniques including angioplasty, embolization, and thrombectomy, tailored to mitigate impediments such as vessel stenosis, abnormal blood flow in AVMs or aneurysms, or the presence of thrombi precipitating acute strokes. Surgical revascularization, another indispensable facet, entails the creation of alternative blood flow pathways to circumvent occluded or constricted cerebral arteries, often via procedures like bypass surgery wherein a healthy vessel is grafted to restore blood flow. In the acute management of strokes, swift intervention assumes paramount importance, entailing the administration of clot-dissolving agents like tissue plasminogen activator (tPA) or the execution of mechanical thrombectomy to extricate occlusive clots and salvage imperiled brain tissue. Beyond acute care, neurovascular interventions also extend their purview to preventive strategies, encompassing the prophylactic treatment of asymptomatic aneurysms or AVMs to preempt the cataclysmic sequelae of rupture or hemorrhage, thereby embodying a comprehensive approach to vascular health within the neurological milieu.
Title : A case of vile vindictive primary CNS vasculitis
George Diaz, Memorial Healthcare Systems, United States
Title : Novel important cellular responses, signaling mechanisms and therapeutic options in vascular dementia
Yong Xiao Wang, Albany Medical College, United States
Title : The role of beliefs, perception, and behavioural patterns in the evolution of psychophysical disorders
Ken Ware, NeuroPhysics Therapy Institute and Research Centre, Australia
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Krishna Moorjani, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling
Abhay Murthy, Boston University, United States
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signalling
Ethan Liu, Boston University, United States