Brain abnormalities refer to discrepancies in the size, structure, or functioning of the brain, or regions within the brain. The abnormalities can be caused by traumatic injuries, infection, or genetic or environmental influences. Abnormalities of the brain can lead to personal, social, and functional disability. The consequences of brain abnormalities can range from relatively minor deficits to severe cognitive, emotional, or physical impairments that require medical intervention and/or life-long care and accommodation. The areas of the brain that are prone to abnormalities include the frontal lobe, the temporal lobe, the parietal lobe, the cerebellum, the brainstem, the basal ganglia, and the limbic system. Each of these regions plays a unique role in controlling our motor, cognitive, and emotional functions. Dysfunction in any of these areas causes deficits in the normal functioning of a person. The frontal lobe is responsible for executive functions such as problem solving and decision making. Disorders that result from damage to this area of the brain include attention deficit disorder, obsessive-compulsive disorder, and bipolar disorder. The temporal lobes are associated with language, memory, and hearing. Impaired functioning of this area can lead to impaired memory and difficulty understanding spoken language. The parietal lobes are important for sensory input, such as touch, pain, or location in space. Damage to this area can lead to disorientation and difficulties perceiving and processing visual, auditory, or other sensory information. The cerebellum is important for controlling balance, coordination, and movement. Damage to this area of the brain can lead to movement disorders like ataxia. The brainstem comprises of several important nuclei that control motor and sensory pathways. Dysfunction of the brainstem can cause paralysis, speech and swallowing problems, and breathing difficulties. Finally, the limbic system is important for the regulation of emotions and drive behaviors. Abnormalities of this area of the brain can cause disturbances in emotions, making a person more prone to aggression or depression. In conclusion, a variety of brain abnormalities can lead to dysfunction of one or multiple regions within the brain, resulting in physical, cognitive or emotional impairments.
Title : Atypical presentation of Juvenile myoclonic epilepsy in a 16-year-old female: A case report
George Diaz, Memorial Healthcare Systems, United States
Title : Triple-network dysfunction, ME/CFS, and the NeuroPhysics Treatment Process “A dynamical systems perspective on psychophysical organization and environmental interaction”
Ken Ware, NeuroPhysics Therapy Institute and Research Centre, Australia
Title : Beyond plaques: 10-nanometer-scale pathoconnectomics of Alzheimer’s disease
Ons M Saad, Panluminate Inc., United States
Title : Results from the global phase 3 trial (IB1001-303) evaluating levacetylleucine in children and adults with ataxia-telangiectasia
Chidinma Ejim, IntraBio, United States
Title : A phase 3, multinational, randomized, placebo-controlled, double-blind, crossover trial (IB1001-304) evaluating levacetylleucine in CACNA1A
Chidinma Ejim, IntraBio, United States
Title : Clinical and molecular phenotype of PTRHD1-associated juvenile parkinsonism
Bhavan A Modi, Barrow Neurological Institute at Phoenix Children's, United States