HYBRID EVENT: You can participate in person at Baltimore, Maryland, USA or Virtually from your home or work.

10th Edition of International Conference on Neurology and Brain Disorders

October 21-23, 2024

October 21 -23, 2024 | Baltimore, Maryland, USA
INBC 2018

Hyun Im Moon

Speaker at Neuroscience Conference - Hyun Im Moon
Bundang Jesaeng Hospital, Korea, Republic of
Title : Culprit Lesions Responsible for Impaired Visual Perception in Post-stroke Patients


Introduction: Visual perception (VP) is a process that involves ‘visual acceptance’ and ‘visual cognition’ through interaction between multiple areas in the human brain. About 35-75% of patients with brain damage have particular impairments in VP that influence the activities of daily living. We aimed to clarify the clinical characteristics that affects on VP and elucidate the lesion location correlated with impaired VP such as visual discrimination, form consistency, visual short term memory, visual closure, spatial orientation assessed with 3rd version of motor-free visual perception test (MVPT-3).

Methods: We reviewed 91 patients with stroke. Clinical assessments such as Korean version of Mini-mental status exam (K-MMSE), MVPT-3, functional independence measure (FIM) were used to evaluate the impairment and limitation of patients after stroke. The patients were divided into 2 groups according to lesioned hemisphere, and we analyzed the differences in characteristics such as demographic factors, lesion factors, cognitive function, and visual perception. Regression analyses were performed to examine the predictors of impaired VP. Lesion location and volume were measured on brain magnetic resonance images. We generated statistic maps of lesions related to impaired VP in swallowing using voxel-based lesion symptom mapping (VLSM).

Results: The group of patients who have right hemispheric lesion had significantly low VP function, especially in subscore of visual discrimination and visual short-term memory. Also, in a regression model, impaired VP was predicted with low K-MMSE, age, and lesioned hemisphere. Using VLSM, we found the lesion location to be associated with impaired VP after adjusting for age and K-MMSE score. Although these results did not reach statistical significance, they showed the lesion pattern with predominant distribution in the right parietal lobe and deep white matter.

Conclusion: Impaired VP in post-stroke patients was not negligible clinically. Patients’ age and cognitive impairments affect the result of VP test. Even when adjusting it, we found a trend that the lesion responsible for impaired VP was located in the right parietal lobe and deep white matter, though the association did not reach significance. It confirms the right hemispheric dominance for VP using VLSM. The deficits in white matter lesion might be related to disconnection of fibers.


Hyun Im Moon is a graduate of Korea University College of medicine. I trained in Physical Medicine and Rehabilitation at the Korea University Medical Center and was board certified in rehabilitation medicine. I started working at Bundang Jesaeng General Hospital. My practice specialized in the neurorehabilitation and electrodiagnosis. My interests also include neuroimaging analysis and prediction of prognosis of brain injured patients such as stroke, TBI. My recently published articles were as follows; “Lesion location associated with balance recovery and gait velocity change after rehabilitation in stroke patients”, “Periventricular White Matter Lesions as a Prognostic Factor of Swallowing Function in Older Patients with Mild Stroke”, “Sonography of Carpal Tunnel Syndrome According to Pathophysiologic Type: Conduction Block Versus Axonal Degeneration” and so on.