HYBRID EVENT: You can participate in person at Orlando, Florida, USA or Virtually from your home or work.

12th Edition of International Conference on Neurology and Brain Disorders

October 20-22, 2025

October 20 -22, 2025 | Orlando, Florida, USA
INBC 2025

Neurofeedback and TPS for severe depression

Speaker at Neurology Conferences - Ioana Ciubotarescu
SAIWALA, Romania
Title : Neurofeedback and TPS for severe depression

Abstract:

Innovative neuromodulation technologies like Neurofeedback and Transcranial Pulse Stimulation (TPS) are offering hope for individuals diagnosed with severe depression. These non-invasive approaches target specific brain regions involved in mood regulation and emotional processing, aiming to bring about lasting changes in mood and well-being.

Neurofeedback uses real-time electroencephalography (EEG) feedback to train individuals to regulate their brainwave patterns. By monitoring brain activity and providing feedback, individuals gain control over their brainwaves, leading to a more balanced and stable mood. TPS utilizes gentle acoustic waves delivered through a headset to stimulate mood-regulating regions of the brain, including the prefrontal cortex and the limbic system. This targeted stimulation promotes neuroplasticity, helping rebalance brain circuits associated with mood regulation highlights the potential of these technologies in addressing the complex brain changes associated with severe depression.

Combining Neurofeedback and TPS creates a powerful synergistic approach, enhancing neuroplasticity and emotional stability. This integrated approach aims to amplify the effects of each technique, creating a more powerful and effective treatment modality for severe depression.

Severe depression is a debilitating condition that can severely impact an individual's daily life, relationships, and overall well-being. Symptoms can include persistent sadness, loss of interest, changes in appetite and sleep patterns, feelings of worthlessness, and thoughts of death or suicide. Individuals suffering from severe depression may struggle to function at work, school, or in their personal lives.

The severity of depression can vary, but severe cases often require specialized treatment approaches. Traditional therapies, such as medication and psychotherapy, may not be sufficient to address the complex underlying brain changes associated with severe depression. Neuromodulation technologies, like Neurofeedback and TPS, adjuncts to conventional treatments, providing a personalized approach that aims to restore brain balance and promote lasting recovery.

Neurofeedback and TPS: Mechanisms

  • Neurofeedback: This non-invasive technique uses real-time EEG feedback to train individuals to regulate brainwave patterns, enhancing mood, attention, and cognitive function. In the context of severe depression, neurofeedback helps individuals regain control over their brainwaves, promoting emotional stability and reducing symptoms like persis
  • Transcranial Pulse Stimulation (TPS): TPS delivers pulses of sound energy that directly impact neural activity, promoting neuroplasticity and rebalancing brain circuits associated with mood regulation. For individuals with severe depression, TPS can help stimulate regions of the brain involved in mood regulation, such as the prefrontal cortex and the limbic system.
  • Synergistic Effect: Combining neurofeedback and TPS creates a powerful synergy that strengthens the capacity for emotional resilience and facilitates lasting changes in mood and well-being. This combined approach can be especially beneficial for individuals with severe depression, as it provides a comprehensive and targeted intervention that addresses both the biological and cognitive aspects of the condition.

Clinical Potential and Outcomes

  • Symptom Reduction and Treatment-Resistant Depression: Neurofeedback and TPS offer a promising approach for individuals experiencing treatment-resistant depression. By targeting brainwave activity and mood-regulating neural pathways, this combination provides a personalized and targeted intervention for persistent depressive symptoms.
  • Functional Recovery and Improved Well-being: Beyond symptom alleviation, the combined neurofeedback and TPS approach promotes functional recovery, enabling individuals to reclaim their sense of well-being and actively engage in activities that bring them joy and fulfillment. The interventions foster neuroplasticity, enhancing the brain's ability to adapt and heal, leading to a more balanced and fulfilling life.
  • Relapse Prevention and Long- Term Stability: A crucial aspect of this approach is relapse prevention. By strengthening cognitive resilience, individuals develop the skills and strategies necessary to manage their emotional well-being over the long term. The intervention empowers individuals to identify early warning signs of depression and take proactive steps to maintain their stability, reducing the risk of future episodes.
  • Severe Depression and Personalized Treatment: For individuals facing severe depression, neurofeedback and TPS provide a highly personalized treatment approach. By identifying specific brainwave patterns associated with severe depressive symptoms, the interventions can be tailored to address the unique needs of each individual. This personalized approach can lead to more effective symptom management and improved overall well-being.

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