Title : Assessment of metabolic syndrome in subjects who have suffered cryptogenic ischemic strokes
Abstract:
Introduction: Stroke is a failure of blood circulaUon that affects a more or less significant area of the brain. There are several risk factors, among which metabolic abnormaliUes seem to play a significant role in its occurrence. Thus, the overall objecUve of our study was to evaluate metabolic syndrome in paUents with cryptogenic ischemic stroke.
Methodology: This is a case-control study including paUents with cryptogenic ischemic stroke. PaUents were recruited at the CHNU/Fann neurological clinic and biological analyses were performed at the biochemistry laboratory of the same facility. Metabolic syndrome was assessed in our enUre study populaUon according to the NCEP ATP III definiUon criteria.
Results: Our study included 40 subjects who had suffered cryptogenic IS and 40 control subjects who had suffered IS with a known cause. The average age of the paUents was 46, with a sex raUo of 1.35. Analysis of the clinical data showed that the incidence of hypertension, diabetes, and dyslipidemia were much higher in ISA of known cause. Assessment of metabolic syndrome revealed frequencies of 12.5% and 56.4% in subjects with cryptogenic ISA and ISA of known cause, respecUvely, according to NCEP criteria.
Conclusion: The results showed that subjects who had suffered cryptogenic IS had fewer cardiovascular risk factors compared to subjects who had suffered IS of known cause. However, significant frequencies of metabolic syndrome determinants were found in cryptogenic IS. Therefore, early screening and regular monitoring of metabolic syndrome in young subjects is necessary.
Keywords: stroke, cryptogenic IS, metabolic syndrome, hypertension, diabetes
