Dr. Yasutoshi Koga is a professor of Pediatrics and Child Health, Kurume University Graduate School of Medicine, Japan. After he finished the research at NCNP, he joined the Mitochondrial Research Group at the Department of Neurology, College of Physicians and Surgeons of Columbia University (Profs. DiMauro S and Schon EA). He discovered a novel therapeutic procedure and has completed the investigator-mediated clinical trial of L-arginine on MELAS in Japan. In 2012, he started the new national project to cure the lactic acidosis. He investigated the new biomarker and develop the diagnostic device of GDF15 for mitochondrial disorders. He has published more than 200 papers in reputed journals.