Myself Sandeep, pursuing my Ph.D. in neurobiology at Jawaharlal Nehru University. I am having passion for research in neurodegenerative disease. Currently I am working on Parkinson’s disease. The in-vivo model that I am working is paraquat-induced Parkinsonism. Parkinson’s disease is a progressive neurological disorder affecting more than 1% of population over age of 60 years. It has motor as well as non-motor symptoms. Aggregation of α- synuclein in the form of Lewy body and loss of dopaminergic neurons in the striatum and substantia nigra region of the brain is pathological hallmark of the disease. Current treatment strategies available are use of L-DOPA or its agonist. But long-term treatment with these results in the bradykinesia, motor fluctuations. So presently no complete cure is available against the disease. I am targeting the molecular pathway involved in the onset and progression of the disease that may open novel treatment strategies against disease.