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Title: THE KLOTHO PROTEIN AND ALZHEIMER’S INTERRELATION

Valentina Barkhanskaya

Karaganda Medical University, Kazakhstan

Biography

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Abstract

Nowadays Klotho protein (KP) is actively researched by scientists but in the textbooks. In databases, many articles about KP, but about Alzheimer disease (AD) and KP were low. Articles in the special medical database can be founded, unfortunately not enough articles about KP and AD interaction. So, the study about the role of KP in AD was interesting.

METHODS

This study included articles from Cochrane library, PubMed, NIH, etc. In order to find out appropriate publications and for the conceptualization of theory keywords such as "Klotho protein", "Alzheimer", "neurodegenerative process", "age-related diseases" were used.

RESULTS

81 articles were studied and 6 (7 percent) of them were selected. Most of them were about klotho protein related to renal and cardiovascular diseases. It means that interaction the KP and AD were studied not well.

CONCLUSION

All publications prove the essential role of KP in neurodegenerative diseases. Because of the lack of information about the function of this protein, the usage of the KP was limited. We consider that in the future this protein will be the part of the therapy in the AD.